Results 211 to 220 of about 3,146,543 (345)

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

High Seroprevalence of <i>Helicobacter pylori</i> and CagA/VacA Virulence Factors in Northern Central America. [PDF]

Gastroenterology Res
Corral JE, Norwood DA, Alvarez CS, Kim DH, Montalvan-Sanchez EE, Rivera-Andrade A, Ramirez-Zea M, McGlynn KA, Waterboer T, Dominguez RL, Morgan DR.   +10 more
europepmc   +1 more source

Novel Mutation in the SLC5A1 Gene Causing Glucose-Galactose Malabsorption: First Confirmed Case From Central America. [PDF]

JPGN Rep, 2023
Katz DT, Curia S, Fifi AC, Febo-Rodriguez L, Llanos-Chea A.   +4 more
europepmc   +1 more source

Biogeographically dynamic genetic structure bridging two continents in the monotypic Central American rodentOtotylomys phyllotis [PDF]

, 2012
Tania A. Gutiérrez-García, Ella Vázquez‐Domínguez   +1 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Triple-target radiosurgery for intractable cancer pain of mixed origin: Two-centre experience in Central America. [PDF]

Br J Pain
Del Cid P, Aquino L, Moreira A, Caceros V, Tobar C, Blanco A, Carvajal G, Bermudez-Guzman L, Lovo EE.   +8 more
europepmc   +1 more source

A modified CALGB 10403 in adolescents and young adults with acute lymphoblastic leukemia in Central America. [PDF]

Blood Adv, 2023
Rangel-Patiño J, Lee-Tsai YL, Urbalejo-Ceniceros VI, Luna-Perez MEM, Espinosa-Bautista KA, Amador LF, Cabrera-García Á, Balderas-Delgado C, Inclan-Alarcon SI, Neme-Yunes Y, Sanchez-Albarrán JM, Apodaca EI, Meillon-García L, Stock W, Demichelis-Gómez R.   +14 more
europepmc   +1 more source

‘The worst thing about hospice is that they talk about death’: contrasting hospice decisions and experience among immigrant Central and South American Latinos with US-born White, non-Latino cancer caregivers

, 2010
Barbara Kreling, Claire Selsky, Monique Perret-Gentil, Elmer Huerta, Jeanne S. Mandelblatt   +4 more
openalex   +2 more sources

Phylogeographical structure within Boa constrictor imperator across the lowlands and mountains of Central America and Mexico [PDF]

, 2014
Marco Suárez‐Atilano, Frank T. Burbrink, Ella Vázquez‐Domínguez   +2 more
openalex   +1 more source

Science, Technology, and Innovation policies in the integration process of Central America and the Dominican Republic: the role of representations and perceptions

, 2022
Víctor Gómez-Valenzuela
openalex   +2 more sources