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Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activation of the renin–angiotensin–aldosterone system, sympathetic nervous system ...
Christina Antza +12 more
wiley +1 more source
Central sleep apnea: misunderstood and mistreated! [version 1; peer review: 2 approved]
Central sleep apnea is prevalent in patients with heart failure, healthy individuals at high altitudes, and chronic opiate users and in the initiation of “mixed” (that is, central plus obstructive apneas).
Jerome A. Dempsey
doaj +1 more source
Clinical and PSG Characteristics Comparison of Central Sleep Apnea in the Elderly and Non-Elderly Patients [PDF]
Guoxin Zhang,1,* Liqin Yang,2,* Fang Zhao,1 Xiaoyun Zhao1 1Respiratory and Critical Care Medicine Department, Tianjin Chest Hospital, Tianjin, People’s Republic of China; 2Institute of Mental Health, Tianjin Anding Hospital, Mental Health Center ...
Zhang G, Yang L, Zhao F, Zhao X
core
Economic evaluations of antiobesity medications: A systematic literature review
The global prevalence of obesity is rising rapidly. With several antiobesity medications approved and many more in development, understanding their economic value is increasingly important. This study reviews full economic evaluations of approved antiobesity medications to assess cost‐effectiveness and inform reimbursement and access decisions.
Martina Jurković +5 more
wiley +1 more source
Aims This study aimed to evaluate the safety, tolerability and pharmacokinetics of a novel oral modified‐release psilocybin formulation (REL‐P11) in normal‐weight and overweight/obese healthy adults and to assess its suitability for controlled, subperceptual exposure, in light of emerging evidence supporting serotonergic modulation in metabolic ...
Anna Signor +11 more
wiley +1 more source
Central Sleep Apnea due to Other Medical Disorders
- Numerous medical disorders can cause central sleep apnea/hypo-ventilation. - This review covers the potential link between brain tumors, Chiari type I malformation, stroke, pain/opioids, endocrine and hormonal disturbances, neurodegenerative disease ...
Martins, Rodrigo Tomazini ; https://orcid.org/ +1 more
core +1 more source
Respiratory derangements, including irregular, tachypnic breathing and central or obstructive apnea can be consequences of seizure activity in epilepsy patients and animal models.
S.M. Villiere +5 more
doaj +1 more source
Diagnostic and therapeutic process of respiratory disorders during sleep
Introduction and purpose Sleep apnea is a disturbance of sleep that affects about 10% of adult population and is not easily detected due to unspecific symptoms.
Karolina Maliszewska +6 more
doaj +1 more source
Continuous positive airway pressure (CPAP) is a standard treatment of moderate and severe obstructive sleep apnea syndrome. However, its effect in patients with coexisting obstructive and central apneas is controversial.
Shereen Farghaly, Alaa Thabet
doaj +1 more source
What Is the Pterygomandibular Raphe? A Confluence of Fasciae Rather Than a Discrete Structure
ABSTRACT The pterygomandibular raphe (PMR) has traditionally been described as a fibrous or tendinous band connecting the bucinator (BM) and superior pharyngeal constrictor (SPCM) muscles. However, recent evidence has questioned its existence. This study aimed to reevaluate the anatomy of the pterygomandibular region by preserving fascial continuity ...
Joe Iwanaga +10 more
wiley +1 more source

