Results 91 to 100 of about 6,431,561 (237)

Hypertension in obesity: A focus on individualized pharmacotherapy and the role of body composition, on behalf of the European Society of Hypertension Working Group on Diabetes and Metabolic Risk Factors and Working Group on Lifestyle, Cardiovascular Pharmacotherapy and Adherence

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activation of the renin–angiotensin–aldosterone system, sympathetic nervous system ...
Christina Antza   +12 more
wiley   +1 more source

Central sleep apnea: misunderstood and mistreated! [version 1; peer review: 2 approved]

open access: yesF1000Research, 2019
Central sleep apnea is prevalent in patients with heart failure, healthy individuals at high altitudes, and chronic opiate users and in the initiation of “mixed” (that is, central plus obstructive apneas).
Jerome A. Dempsey
doaj   +1 more source

Clinical and PSG Characteristics Comparison of Central Sleep Apnea in the Elderly and Non-Elderly Patients [PDF]

open access: yes
Guoxin Zhang,1,* Liqin Yang,2,* Fang Zhao,1 Xiaoyun Zhao1 1Respiratory and Critical Care Medicine Department, Tianjin Chest Hospital, Tianjin, People’s Republic of China; 2Institute of Mental Health, Tianjin Anding Hospital, Mental Health Center ...
Zhang G, Yang L, Zhao F, Zhao X
core  

Economic evaluations of antiobesity medications: A systematic literature review

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
The global prevalence of obesity is rising rapidly. With several antiobesity medications approved and many more in development, understanding their economic value is increasingly important. This study reviews full economic evaluations of approved antiobesity medications to assess cost‐effectiveness and inform reimbursement and access decisions.
Martina Jurković   +5 more
wiley   +1 more source

Pharmacokinetics and safety of a modified‐release psilocybin formulation: A SAD Phase I trial in normal‐weight and overweight/obese participants

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to evaluate the safety, tolerability and pharmacokinetics of a novel oral modified‐release psilocybin formulation (REL‐P11) in normal‐weight and overweight/obese healthy adults and to assess its suitability for controlled, subperceptual exposure, in light of emerging evidence supporting serotonergic modulation in metabolic ...
Anna Signor   +11 more
wiley   +1 more source

Central Sleep Apnea due to Other Medical Disorders

open access: yes, 2014
- Numerous medical disorders can cause central sleep apnea/hypo-ventilation. - This review covers the potential link between brain tumors, Chiari type I malformation, stroke, pain/opioids, endocrine and hormonal disturbances, neurodegenerative disease ...
Martins, Rodrigo Tomazini ; https://orcid.org/   +1 more
core   +1 more source

Seizure-associated central apnea in a rat model: Evidence for resetting the respiratory rhythm and activation of the diving reflex

open access: yesNeurobiology of Disease, 2017
Respiratory derangements, including irregular, tachypnic breathing and central or obstructive apnea can be consequences of seizure activity in epilepsy patients and animal models.
S.M. Villiere   +5 more
doaj   +1 more source

Diagnostic and therapeutic process of respiratory disorders during sleep

open access: yesJournal of Education, Health and Sport
Introduction and purpose Sleep apnea is a disturbance of sleep that affects about 10% of adult population and is not easily detected due to unspecific symptoms.
Karolina Maliszewska   +6 more
doaj   +1 more source

Role of continuous positive airway pressure in patients with combined sleep apnea syndrome without congestive heart failure

open access: yesEgyptian Journal of Chest Disease and Tuberculosis, 2016
Continuous positive airway pressure (CPAP) is a standard treatment of moderate and severe obstructive sleep apnea syndrome. However, its effect in patients with coexisting obstructive and central apneas is controversial.
Shereen Farghaly, Alaa Thabet
doaj   +1 more source

What Is the Pterygomandibular Raphe? A Confluence of Fasciae Rather Than a Discrete Structure

open access: yesClinical Anatomy, EarlyView.
ABSTRACT The pterygomandibular raphe (PMR) has traditionally been described as a fibrous or tendinous band connecting the bucinator (BM) and superior pharyngeal constrictor (SPCM) muscles. However, recent evidence has questioned its existence. This study aimed to reevaluate the anatomy of the pterygomandibular region by preserving fascial continuity ...
Joe Iwanaga   +10 more
wiley   +1 more source

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