Results 61 to 70 of about 6,302,413 (368)

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

Aging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal, Abhimanyu Chiraparambil Radhakrishnan, Ayanchetty Haripraba, Saif Syed, Gajawada Pragna, Ayush Dwivedi, Akash Rawat, Daniela Castro Calderón, Martin Cevallos‐Cueva   +8 more
wiley   +1 more source

Crime Against History: Slavery, Race, and the 1776 Report

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT With the 2025 executive order, “Ending Radical Indoctrination in K‐12 Schooling,” the Trump administration reestablished the 1776 Commission, which produced The 1776 Report. This article argues that this report, which is an unsubtle response to The 1619 Project, reveals how White Christian Nationalists wish to mandate that a hyper‐patriotic ...
William V. Trollinger
wiley   +1 more source

A Reanalysis of Eurasian Population History: Ancient DNA Evidence of Population Affinities [PDF]

Human Biology. (2006). 78: 413-440, 2011
Mitochondrial hypervariable region I genetic data from ancient populations at two sites from Asia, Linzi in Shandong (northern China) and Egyin Gol in Mongolia, were reanalyzed to detect population affinities. Data from a total of 51 modern populations were used to generate distance measures (Fst's) to the two ancient populations.
arxiv   +1 more source

Detecting human influence on the temperature changes in Central Asia

Climate Dynamics, 2019
The ecosystem and societal development in arid Central Asia are highly vulnerable to climate change. During the past five decades, significant warming occurs in Central Asia, but whether the influence of anthropogenic forcing is detectable remains ...
Dongdong Peng, Tianjun Zhou, Lixia Zhang, Liwei Zou   +3 more
semanticscholar   +1 more source

Radiotherapy medical physics in the Philippines: A contemporary overview

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose With cancer ranking as the third leading cause of death in the Philippines and a disparity in healthcare resources across regions, this research aimed to assess the state of radiotherapy medical physics in the country. Methodology The study utilized a comprehensive online survey with 94 structured questions answered by 19 clinics ...
John Paul C. Cabahug, Ramon Carlo Cruzpero, Luis E. Fong de los Santos, Eric C. Ford, Afua A. Yorke   +4 more
wiley   +1 more source

Dyadospheres Don't Develop [PDF]

, 2006
Pair production itself prevents the development of dyadospheres, hypothetical macroscopic regions where the electric field exceeds the critical Schwinger value. Pair production is a self-regulating process that would discharge a growing electric field, in the example of a hypothetical collapsing charged stellar core, before it reached 6% of the minimum
arxiv   +1 more source

A Global Tropical Survey of Mid-Tropospheric Cyclones [PDF]

, 2020
Mid-Tropospheric Cyclones (MTCs) are moist synoptic systems with distinct mid tropospheric vorticity maxima and weak signatures in the lower troposphere. Composites and statistics of MTCs over the tropics are constructed and compared with monsoon lows and depressions (together, lower troposphere cyclones; LTCs). We begin with South Asia, where tracking
arxiv   +1 more source

Mitochondrial DNA disorders in neuromuscular diseases in diverse populations

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Neuromuscular features are common in mitochondrial DNA (mtDNA) disorders. The genetic architecture of mtDNA disorders in diverse populations is poorly understood. We analysed mtDNA variants from whole‐exome sequencing data in neuromuscular patients from South Africa, Brazil, India, Turkey and Zambia. In 998 individuals, there were two definite
Fei Gao, Katherine R Schon, Jana Vandrovcova, Özlem Yayıcı Köken, Sharika Raga, Kireshnee Naidu, Maryke Schoonen, Nimita Rani, Pedro Tomaselli, Dipti Baskar, Musambo Kapapa, Ipek Polat, Lindsay A Wilson, Kumarasamy Thangaraj, Uluç Yiş, Bevinahalli N Nandeesh, David Bearden, Michelle Kvalsund, Franclo Henning, Seena Vengalil, Atchayaram Nalini, Claudia F. R. Sobreira, Wilson Marques, Haluk Topoloğlu, Michael G Hanna, Sireesha Yareeda, Venugopalan Y Vishnu, Francois H van der Westhuizen, Izelle Smuts, Surita Meldau, Jo Wilmshurst, Büşranur Çavdarlı, Jeannine Heckmann, Patrick F Chinnery, Rita Horvath   +34 more
wiley   +1 more source

Echinococcus granulosus cyst fluid inhibits inflammatory responses through inducing histone demethylase KDM5B in macrophages

Parasites & Vectors, 2023
Background Echinococcus granulosus cyst fluid (EgCF) weakens macrophage inflammatory responses, thereby enabling the parasite to evade the immune system. However, the role of histone modification in this process remains to be explored. Methods The levels
Xiaopeng Wang, Ruolin Lin, Chunxue Fu, Chun Yang, Dan Dong, Xiangwei Wu, Xueling Chen, Lianghai Wang, Jun Hou   +8 more
doaj   +1 more source