Results 261 to 270 of about 356,326 (313)

Master Regulator SMC1A, Stabilized by N6‐Methyladenosine Reader IGF2BP1, Promotes HCC Progression Through Facilitating Enhancer–Promoter Interaction of Nestin

open access: yesAdvanced Science, EarlyView.
IGF2BP1‐mediated m6A stabilization sustains SMC1A expression, enabling cohesin‐associated chromatin regulation of Nestin in hepatocellular carcinoma. This work reveals an epitranscriptomic‐chromatin‐cytoskeletal regulatory axis linked to malignant phenotypes and identifies SMC1A as a biologically relevant vulnerability in HCC.
Zhenxiang Peng   +7 more
wiley   +1 more source

Mechanism‐Informed Machine Learning Enables Discovery of Oncolytic Peptides for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
MISPOP integrates ensemble learning with membrane‐active physicochemical priors to identify Dermaseptin‐S9, a natural oncolytic peptide that disrupts tumor membranes, triggers immunogenic cell death, and shows strong antitumor activity. The study illustrates a mechanism‐informed route from peptide sequence data to cancer immunotherapy leads.
Wen Zhang   +11 more
wiley   +1 more source

Correction to: Optimizing a feasible protocol for acellular nerve allografts: An experimental study. [PDF]

open access: yesCell Tissue Bank
de Juan Marín M   +5 more
europepmc   +1 more source

Establishment of Serum 25-Hydroxyvitamin D Reference Range for Healthy Adult Men Not Using Vitamin D Supplements in Alqurayyat, Saudi Arabia. [PDF]

open access: yesInt J Gen Med
Aldaham AMS   +10 more
europepmc   +1 more source

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