Results 1 to 10 of about 6,142 (181)

C53 Interacting with UFM1-Protein Ligase 1 Regulates Microtubule Nucleation in Response to ER Stress [PDF]

open access: yesCells, 2022
ER distribution depends on microtubules, and ER homeostasis disturbance activates the unfolded protein response resulting in ER remodeling. CDK5RAP3 (C53) implicated in various signaling pathways interacts with UFM1-protein ligase 1 (UFL1), which ...
Stanislav Vinopal   +2 more
exaly   +6 more sources

A Novel C53/LZAP-interacting Protein Regulates Stability of C53/LZAP and DDRGK Domain-containing Protein 1 (DDRGK1) and Modulates NF-κB Signaling [PDF]

open access: yesJournal of Biological Chemistry, 2010
C53/LZAP (also named as Cdk5rap3) is a putative tumor suppressor that plays important roles in multiple cell signaling pathways, including DNA damage response and NF-kappaB signaling. Yet how its function is regulated remains largely unclear. Here we report the isolation and characterization of two novel C53/LZAP-interacting proteins, RCAD (Regulator ...
Honglin Li
exaly   +3 more sources

Forecasting realized volatility through financial turbulence and neural networks

open access: yesEconomics and Business Review, 2023
This paper introduces and examines a novel realized volatility forecasting model that makes use of Long Short-Term Memory (LSTM) neural networks and the risk metric financial turbulence (FT).
Souto Hugo Gobato, Moradi Amir
doaj   +1 more source

A cross-kingdom conserved ER-phagy receptor maintains endoplasmic reticulum homeostasis during stress

open access: yeseLife, 2020
Eukaryotes have evolved various quality control mechanisms to promote proteostasis in the endoplasmic reticulum (ER). Selective removal of certain ER domains via autophagy (termed as ER-phagy) has emerged as a major quality control mechanism.
Madlen Stephani   +28 more
doaj   +1 more source

MCMC and GLMs for estimating regression parameters: Evidence from non-life Egyptian insurance sector [PDF]

open access: yesJournal of Humanities and Applied Social Sciences, 2019
Purpose – The purpose of this study is to estimate the linear regression parameters using two alternative techniques. First technique is to apply the generalized linear model (GLM) and the second technique is the Markov Chain Monte Carlo (MCMC) method ...
Mahmoud ELsayed, Amr Soliman
doaj   +1 more source

Value-at-risk predictive performance: a comparison between the CaViaR and GARCH models for the MILA and ASEAN-5 stock markets [PDF]

open access: yesJournal of Economics Finance and Administrative Science, 2021
Purpose – This paper tests the accuracies of the models that predict the Value-at-Risk (VaR) for the Market Integrated Latin America (MILA) and Association of Southeast Asian Nations (ASEAN) emerging stock markets during crisis periods.
Ramona Serrano Bautista   +1 more
doaj   +1 more source

Deep Learning Predictive Models for Terminal Call Rate Prediction during the Warranty Period

open access: yesBusiness Systems Research, 2020
Background: This paper addresses the problem of products’ terminal call rate (TCR) prediction during the warranty period. TCR refers to the information on the amount of funds to be reserved for product repairs during the warranty period.
Ferencek Aljaž   +4 more
doaj   +1 more source

The impact of COVID-19 outbreak on the Mauritian export trade: a disaggregated analysis [PDF]

open access: yesInternational Trade, Politics and Development, 2022
Purpose – This study aims at evaluating the effect of the COVID-19 pandemic on the export trade system for Mauritius during the first half of 2020 (January 2020–June 2020).
Zameelah Khan Jaffur   +5 more
doaj   +1 more source

Nonlinear optimisation approach to proposing novel Croatian Industrial Confidence Indicator

open access: yesCroatian Review of Economic, Business and Social Statistics, 2019
Croatian Industrial Confidence Indicator (ICI) is one of the measures of mangers’ sentiment about the economic situation in the Croatian manufacturing industry. Since 2005, the ICI has been calculated in accordance with the harmonised European Commission
Čižmešija Mirjana   +2 more
doaj   +1 more source

An Approach for the In-Depth Data Analysis of the Marine Traffic of Independent Nearby Ports

open access: yesFolia Oeconomica Stetinensia, 2023
Maritime transport helps the development of the economy of countries. Improving the current situation in this type of transport requires the application of modern software tools for assessment, analysis and forecasting.
Vasilev Julian, Sulova Snezhana
doaj   +1 more source

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