Results 111 to 120 of about 97,613 (280)

Identification of ferroptosis‐related genes involved in chronic obstructive pulmonary disease based on bioinformatics analysis

Animal Models and Experimental Medicine, EarlyView.
The design of the entire paper. Green part represents the bioinformatics analysis approach. Yellow part represents the ideas of animal experiment. Abstract Background Chronic obstructive pulmonary disease (COPD) is a type of chronic respiratory disease.
Xuejing Luan, Jinghui Xie, Lu Zhang, Xiao Ma, Lichangtian Jiao, Jie Zhu   +5 more
wiley   +1 more source

Depression Polygenicity and Disease Activity and Disability Worsening in Multiple Sclerosis

Annals of Neurology, EarlyView.
Objective A better understanding of factors associated with multiple sclerosis (MS) disease activity and disability is needed. Given the strong link between comorbid depression and MS disease activity and disability, we aimed to determine whether the depression genetic burden, as modelled using its polygenic score, is associated with MS disease ...
Ali Manouchehrinia, Kathryn C. Fitzgerald, Amber Salter, Ruth Ann Marrie, Lars Alfredsson, Charles N. Bernstein, James M. Bolton, Gary Cutter, John D. Fisk, Lesley A. Graff, Carol A. Hitchon, Jan Hillert, Ingrid Kockum, Yi Lu, Fred D. Lublin, Kyla McKay, Tomas Olsson, Scott Patten, Amit Patki, Hayley Riel, Klementy Shchetynsky, Pernilla Stridh, Hemant K. Tiwari, Jerry S. Wolinsky, Kaarina Kowalec   +24 more
wiley   +1 more source

Comparative Safety Profiles of Ocrelizumab and Rituximab in Multiple Sclerosis Treatment Using Real‐World Evidence

Annals of Neurology, EarlyView.
Objective The objective of this study was to compare the long‐term safety profiles of ocrelizumab and rituximab in persons with multiple sclerosis (MS). Methods Using retrospective data from the University of California (UC) Health System, we simulated a target clinical trial. The primary cohort from UC San Francisco (UCSF) and a validation cohort from
Gabriel Cerono, Bruce A.C. Cree, Stephen L. Hauser, Sergio E. Baranzini   +3 more
wiley   +1 more source

Identifying Predictive Biomarkers of Response in Patients With Rheumatoid Arthritis Treated With Adalimumab Using Machine Learning Analysis of Whole‐Blood Transcriptomics Data

Arthritis &Rheumatology, EarlyView.
Objective Tumornecrosis factor inhibitors (TNFi) have significantly improved rheumatoid arthritis (RA) management, yet variability in patient response remains a substantial challenge, with approximately 40% of patients discontinuing TNFi due to nonresponse or adverse effects.
Chuan Fu Yap, Nisha Nair, Ann W. Morgan, John D. Isaacs, Anthony G. Wilson, Kimme Hyrich, Guillermo Barturen, María Riva‐Torrubia, Marta Gut, Ivo Gut, Marta E. Alarcón Riquelme, Anne Barton, Darren Plant   +12 more
wiley   +1 more source

Central and local limit theorems for the coefficients of polynomials of binomial type

Journal of Combinatorial Theory, Series A, 1977
AbstractWe introduce the problem of establishing a central limit theorem for the coefficients of a sequence of polynomials Pn(x) of binomial type; that is, a sequence Pn(x) satisfying exp(xg(u)) = ∑n=0∞ Pn(x)(unn!) for some (formal) power series g(u) lacking constant term.
openaire   +3 more sources

Alu Overexpression Leads to an Increased Double‐stranded RNA Signature in Dermatomyositis

Arthritis &Rheumatology, Accepted Article.
Objective Dermatomyositis is an autoimmune condition characterized by a high interferon signature of unknown etiology. Because coding sequences constitute <1.2% of our genomes, there is a need to explore the role of the non‐coding genome in disease pathogenesis.
Rayan Najjar, Andrew Mammen, Tomas Mustelin   +2 more
wiley   +1 more source

Longitudinal links of negative student–teacher relationships and positive class climate with traditional bullying and cyberbullying perpetration

British Educational Research Journal, EarlyView.
Abstract The current study aimed to investigate whether negative student–teacher relationships and within‐class perceptions of the class climate at the individual level, and positive class climates at the classroom level in fifth grade, were associated with traditional bullying and cyberbullying perpetration 1 year later, in sixth grade, in a sample of
Robert Thornberg, Björn Sjögren, Jun Sung Hong, Claudio Longobardi   +3 more
wiley   +1 more source

Greening the Narrative: How Organizational Culture Impacts Environmental Disclosures

Business Strategy and the Environment, EarlyView.
ABSTRACT In light of existential dangers to our planet, the urgency to reevaluate corporate practices has never been more palpable. With an emphasis on disclosures, this groundbreaking research sets out to analyze the complex relationship between corporate culture and its significant influence on environmental sustainability within firms.
Gurmani Chadha, Monica Singhania, Shikha Gupta   +2 more
wiley   +1 more source

An Investigation of Hyperostosis Frontalis Interna in a Modern Anatomical Body Donor Population

Clinical Anatomy, EarlyView.
ABSTRACT This research sought to examine the prevalence and severity of hyperostosis frontalis interna (HFI) in the Chicagoland anatomical body donor population. The study further aimed to elucidate potential demographic risk factors for HFI, including sex, age at death, and structural vulnerability index (SVI), as well as any common comorbidities, as ...
Amy C. Beresheim, Amanda Hall
wiley   +1 more source

On Some Series Involving the Central Binomial Coefficients

15 ...
Adegoke, Kunle, Frontczak, Robert, Goy, Taras   +2 more
openaire   +2 more sources