Results 141 to 150 of about 100,720 (284)

Chronic Low‐Dose Unsymmetrical Dimethylhydrazine Exposure in Rats: Multiorgan Mechanisms and Biomarker Identification

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Unsymmetrical dimethylhydrazine (UDMH), a highly toxic rocket propellant with known multiorgan effects, requires urgent characterization of its chronic low‐dose toxicity. Using an integrated approach including exploratory transcriptomics (n = 3/group) and metabolomic (n = 4/group) approaches in male Sprague–Dawley rats exposed to high‐dose ...
Fuzhou Liu   +6 more
wiley   +1 more source

Exogenous Melatonin and Sleep Quality: A Scoping Review of Systematic Reviews

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Melatonin is increasingly used to treat sleep disturbances, yet its overall efficacy remains unclear due to variability in existing evidence. This scoping review aimed to synthesize systematic reviews with meta‐analyses assessing the effects of exogenously administered melatonin on sleep quality in humans.
Samyuktha Iyer   +3 more
wiley   +1 more source

Adolescents' trajectories of mental health in the MYRIAD trial

open access: yesJCPP Advances, EarlyView.
Abstract Background This study explored adolescent's mental health trajectories over the course of a school‐based mindfulness‐based intervention trial (MYRIAD). It examined whether intervention condition (mindfulness vs. teaching‐as‐usual), individual‐level and contextual‐level factors were associated with different trajectories.
Carolina Guzman Holst   +8 more
wiley   +1 more source

Patterns of help‐seeking for mental health problems in 1001 self‐identified neurodivergent adolescents who self‐harm

open access: yesJCPP Advances, EarlyView.
Adolescents who self‐harm are also more likely to seek support from informal than formal sources and least likely to seek support online. But neurodivergent adolescents who self‐harm are more likely to seek any and especially formal (pastoral school staff or mental health services) support than their peers.
Simona Skripkauskaite   +4 more
wiley   +1 more source

The Individual and Combined Effects of Warming and Atrazine on Lithobates pipiens Phenotypes: Implications for Frog Declines

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Amphibians are the most threatened vertebrate class globally. Climate change, agrochemicals, and/or pathogens and parasites are implicated in contributing to amphibian declines, either singly or in combination. We investigated individual and combined effects of elevated temperatures and atrazine (2.0 μg/L) on Lithobates [formerly Rana] pipiens
Melody J. Gavel   +7 more
wiley   +1 more source

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