Results 71 to 80 of about 165,625 (255)
Advanced Science, EarlyView.ABSTRACT The intricate interplay between chronic psychological stress and periodontitis, mediated by oral microbiota and macrophage polarization, remains largely enigmatic. Here, we demonstrate that chronic restraint stress (CRS) exacerbates periodontitis by inducing oral microbial dysbiosis and a consequential shift in host metabolism.
Shihong Luo +13 more
wiley +1 more source
Haplotype‐Resolved 3D Genomic Landscapes and Their Impacts on Agronomic Traits in Grapevine
Advanced Science, EarlyView.This study presents a haplotype‐resolved 3D genomic landscape of grapevine, revealing that structural variations (SVs) are closely associated with phased topologically associating domain (TAD) boundary transitions. These rearrangements coordinate with allele‐specific DNA methylation (ASM) and allele‐biased gene expression (ASE) to shape key agronomic ...
Yanling Peng +18 more
wiley +1 more source
Advanced Science, EarlyView.After liver transplantation, ischemia‐reperfusion injury is more severe in pericentral regions. Multiomic analyses of human grafts and mouse models identify FOXO1 activation in pericentral hepatocytes as an upstream driver of SAA secretion. SAA recruits and activates FPR2+ macrophages, amplifying local inflammation. Amilo‐5MER inhibits SAA bioactivity,
Feng Zhang +19 more
wiley +1 more source
Sums of Reciprocals of the Central Binomial Coefficients
, 2006 We consider a set of combinatorial sums involving the reciprocals of the central binomial coefficients and try to solve (or close) them by means of generating functions. We obtain a number of results for infinite sums, in some of which the golden ratio ! appears.
openaire +3 more sources
Advanced Science, EarlyView.A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...
Yoo Min Park +11 more
wiley +1 more source
A Note on Extended Binomial Coefficients
, 2014 We study the distribution of the extended binomial coefficients by deriving a complete asymptotic expansion with uniform error terms. We obtain the expansion from a local central limit theorem and we state all coefficients explicitly as sums of Hermite ...
Neuschel, Thorsten
core
Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES
Advanced Science, EarlyView.In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu +5 more
wiley +1 more source
Mixed Parity Variants of Apéry-Type Binomial Series and Level Four Colored Multiple Zeta Values
MathematicsIn this paper, we study an Apéry-type series involving the central binomial coefficients ∑n1>…>nd>014n12n1n1n1−s1…nd−sd and its variations where the summation indices may have mixed parities and some or all “>” are replaced by “≥”, as long as the series ...
Ce Xu, Jianqiang Zhao
doaj +1 more source
Biolipid Film‐Fused Electrochemiluminescence for Multipurpose In Situ Bioassays
Advanced Science, EarlyView.An ECL‐emissive, membrane‐interactive scaffold was fabricated, and facilely fused with natural and non‐native phospholipids into multifactorial mimicries of cytomembranes and vesicles for in vitro representative membrane‐process probing. Such a biointerface‐based, state‐sensitive ECL paradigm not only pinpointed proximal phenomena, including channeling
Jialiang Chen +9 more
wiley +1 more source
On Some Series Involving the Central Binomial Coefficients
15 ...
Adegoke, K., Frontczak, R., Goy, T.
openaire +2 more sources