Results 41 to 50 of about 6,367,918 (301)

Relationship Between Cervical Central Canal and Neural Foraminal Dimensions in a Normative Population

open access: yesTomography
Background/Objectives: The relationship between cervical central canal and neural foraminal dimensions remains undefined. This study examined correlations between these structures in a young adult CT cohort screened to exclude apparent cervical spinal ...
Kai Nguyen   +9 more
doaj   +1 more source

Topography of the incisive canal and features of its location relative to the incisors and canines of the upper jaw

open access: yesИзвестия высших учебных заведений. Поволжский регион: Медицинские науки, 2022
Background. It is important to take into account proximity of the incisors’ and canines’ dental alveoli to the incisive canal during immediate implant to prevent injury of the naso-palatine nerve.
O.V. Kalmin, O.O. Ilyunina
doaj   +1 more source

ALGAL FLORA OF CENTRAL ASIAN CANALS

open access: yes, 2023
Information about the algal flora of Central Asian canals is insufficient. However, modern research has shown that they have great importance and that the algae have an indicative level of biosecurity and bioecology. That is why the study of the algae of the Central Asian channels has been the main goal.
openaire   +2 more sources

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Intranasal scopolamine affects the semicircular canals centrally and peripherally

open access: yesJournal of Applied Physiology, 2015
Space motion sickness (SMS), a condition caused by an intravestibular conflict, remains an important obstacle that astronauts encounter during the first days in space. Promethazine is currently the standard treatment of SMS, but scopolamine is used by some astronauts to prevent SMS.
Weerts, Aurélie P.   +6 more
openaire   +4 more sources

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

open access: yesMolecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Home - About - Disclaimer - Privacy