Results 61 to 70 of about 6,367,918 (301)

The influence of dilacerated impacted maxillary central incisors on the incisive canal and nasal cavity characteristics: a retrospective comparative study

open access: yesBMC Oral Health
Background Dental anomalies significantly impact oral structures, particularly impacted maxillary central incisors. These anomalies can complicate interactions with nearby anatomical features like the incisive canal and nasal cavity.
Enas Senan Alyafrusee   +7 more
doaj   +1 more source

Comparative Analysis of Root Canal Morphology in Human Mandibular Permanent Incisors using Decalcification Technique and Periapical Radiographs: An In-vitro Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Introduction: Understanding the intricate root canal system of mandibular incisors is crucial for successful root canal therapy. Variations in canal anatomy pose challenges in diagnosis and treatment planning, emphasising the need for comprehensive ...
Surendra Nath Tudu   +5 more
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

open access: yesFEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar   +11 more
wiley   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla   +10 more
wiley   +1 more source

Root canal morphology of permanent mandibular incisors of Saudi subpopulation in Al-Baha region: A cone-beam computed tomography study

open access: yesSaudi Endodontic Journal
Introduction: A proper understanding of root canal morphology and its deviations is essential for improving the outcomes of endodontic procedures. Therefore, the current study aims to explore the root canal morphology of permanent mandibular central and ...
Mohammed S. Alzahrani   +7 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Stretching Morphogenesis of the Roof Plate and Formation of the Central Canal

open access: yesPLoS ONE, 2013
Neurulation is driven by apical constriction of actomyosin cytoskeleton resulting in conversion of the primitive lumen into the central canal in a mechanism driven by F-actin constriction, cell overcrowding and buildup of axonal tracts. The roof plate of the neural tube acts as the dorsal morphogenetic center and boundary preventing midline crossing by
Kondrychyn, I.   +3 more
openaire   +4 more sources

Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park   +5 more
wiley   +1 more source

The interoceanic canal project in Nicaragua and the influence of Chinese capitals in Central America

open access: yesRevista Conjuntura Austral, 2018
This article analyzes the interoceanic canal project in Nicaragua related to Chinese capitals in Central America, recovering some theoretical interpretations of the capitalist dynamics.
Paula Daniela Fernández   +1 more
doaj   +1 more source

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