Results 161 to 170 of about 944,652 (357)

FORMAS DEL TERRENO Y DEPOSITOS CUATERNARIOS, TIERRA DEL FUEGO CENTRAL, CHILE [PDF]

, 2010
L. D. Raedeke
openalex   +1 more source

TRIM38 Suppresses Breast Cancer Progression via Modulating SQSTM1 Ubiquitination and Autophagic Flux

Advanced Science, EarlyView.
TRIM38, an E3 ubiquitin ligase, suppresses breast cancer progression by inhibiting proliferation, migration, and invasion. Downregulated in breast tumor, its loss correlates with poor prognosis. Mechanistically, TRIM38 mediates K63‐linked ubiquitination of SQSTM1/p62 at K420, disrupting SQSTM1‐LC3 interaction and blocking autophagic flux.
Shan Jiang, Lijuan Wang, Dianwen Han, Peng Su, Bing Chen, Wenjing Zhao, Tong Chen, Ning Zhang, Xiaolong Wang, Yiran Liang, Yaming Li, Chen Li, Xi Chen, Dan Luo, Qifeng Yang   +14 more
wiley   +1 more source

Late Holocene summer temperatures in the central Andes reconstructed from the sediments of high-elevation Laguna Chepical, Chile (32° S)

, 2013
Rixt de Jong, Lucien von Gunten, Antonio Maldonado, Martín Grosjean   +3 more
openalex   +1 more source

Is the jet-drive flute model able to produce modulated sounds like Flautas de Chinos ?

, 2013
Flautas de chinos - prehispanic chilean flutes played during ritual celebrations in central Chile - are known to produce very particular beating sounds, the so-called sonido rajado.
De La Cuadra, Patricio, Fabre, Benoît, Terrien, Soizic, Vergez, Christophe   +3 more
core   +1 more source

Immunomodulatory Hydrogel Coating with SeNPs and Lithium Silicate Synergistically Promotes Osseointegration and Prevents Infection on Titanium Implants

Advanced Science, EarlyView.
This study introduces a multifunctional hydrogel coating (Lap‐CMCSMA/GelMA@SeNPs) that scavenges ROS, modulates immune responses, and shows strong antibacterial activity. It effectively restores the peri‐implant microenvironment. The coating exhibits excellent biocompatibility and promotes osteogenic differentiation.
Su Jiang, Baisheng Cai, Cong Ye, Kefan Wu, Kuan Liu, Pengcheng Xu, Fan Liu, Yake Liu   +7 more
wiley   +1 more source

Filarial nematodes in domestic dogs and mosquitoes (Diptera: Culicidae) from semi-rural areas in Central Chile. [PDF]

Front Vet Sci, 2023
Cancino-Faure B, González CR, Piñeiro González A, Pinochet S, Bustos S, Morchón R, Piñeiro Cazaux A, Quezada Aguilar I, Salas Espinoza M, Acevedo Salgado R, Barra Díaz C, Segovia C, Lozada-Yavina R, Álvarez Rojas CA.   +13 more
europepmc   +1 more source

A Modular Vaccine Platform Against SARS‐CoV‐2 Based on Self‐Assembled Protein Nanoparticles

Advanced Science, EarlyView.
A modular BP26 nanoparticle vaccine platform incorporating the SpyTag/SpyCatcher system enables high‐density, repetitive antigen display with post‐expression flexibility. Conjugation of the SARS‐CoV‐2 RBD to BP26 nanoparticles elicits strong humoral immunity and confers protection against viral challenge in vivo.
Seojung Lee, Yejin Jang, Yujin Kim, Yumi Shin, Ji‐Joon Song, Meehyein Kim, Sangyong Jon   +6 more
wiley   +1 more source

Aríbalo Inca de Chile Central

, 2018
MNHNcl
openalex   +1 more source

HSP70 Interactome‐Mediated Proteolysis Targeting Chimera (HSP70‐PROTAC) for Ferroptosis‐Driven Cancer Treatment

Advanced Science, EarlyView.
This study reports a novel targeted protein degradation strategy termed “HSP70‐PROTAC” that recruits Hsc70 complex to a target protein for inducing degradation. Among them, GDAz‐3 exhibits effective GPX4 degradation activity via UPS/CMA processes, triggering ferroptosis‐driven anticancer activity in vitro and in vivo.
Jinyun Dong, Yulong Li, Hui Liang, Zumei Wu, Shiqun Wang, Yichao Wang, Jieyu Xu, Yanning Lan, Maohua Cai, Guangzhao Pan, Haiyan Yang, Kai Miao, Zhe‐Sheng Chen, Fangfang Tao, Xuelei Ma, Jiang‐Jiang Qin   +15 more
wiley   +1 more source

Magmatic differentiation at La Poruña scoria cone, Central Andes, northern Chile: Evidence for assimilation during turbulent ascent processes, and genetic links with mafic eruptions at adjacent San Pedro volcano

, 2019
Osvaldo González-Maurel, Benigno Godoy, Petrus le Roux, Inés Rodríguez, Carolina Marín, Andrew Menzies, Daniel Bertín, Diego Morata, Marina Vargas   +8 more
openalex   +2 more sources