Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
A preclinical setup for FLASH radiotherapy beam delivery at isocenter using downstream electron scattering. [PDF]
Ozoemelam I +4 more
europepmc +1 more source
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
A Fast and Efficient Method for Radiation Pattern Prediction in Large-Scale Tightly Coupled Linear Antenna Arrays. [PDF]
Wei J, Xu P, Lu H, Cai X.
europepmc +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Denis pattern-dependent biomechanical behavior of posterior trans-iliac plate fixation compared with bilateral triangular osteosynthesis in unilateral sacral fractures: a finite element study. [PDF]
Yang J +6 more
europepmc +1 more source
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
Comparative analysis of temperature effect on bandgap characteristics in 1D phononic crystals: Periodic versus quasiperiodic structures. [PDF]
Heravi FJ +9 more
europepmc +1 more source
Impact of gap anisotropy of Polar and Anderson-Brinkman-Morel p-wave superconductors on thermoelectric properties of quantum dot hybrids. [PDF]
Sonar V, Trocha P.
europepmc +1 more source
Analysis of root canal anatomy configuration in permanent anterior teeth among the Pakistani subpopulations using cone-beam CT. [PDF]
Karobari MI +8 more
europepmc +1 more source

