Results 81 to 90 of about 61,040 (294)

Herpes simplex keratitis: Challenges in diagnosis and clinical management [PDF]

, 2017
Herpes simplex virus is responsible for numerous ocular diseases, the most common of which is herpetic stromal keratitis. This is a recurrent infection of the cornea that typically begins with a subclinical infection of the cornea that establishes a ...
Azher, Tayaba N, Huang, Andrew JW, Stuart, Patrick M, Tajfirouz, Deena, Yin, Xiao-Tang   +4 more
core   +3 more sources

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

Advanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi, Andrew E. Miller, Li Diao, Xinying Guo, Natalie Andonian, Elham Karimizadeh, Thomas H. Barker, Boris Hinz   +7 more
wiley   +1 more source

Comparison of Corneal Thickness in Candidates for Photorefractive Keratectomy (PRK) Using Three Methods, Orbscan II, Pentacam, and Ultrasound

مجله دانشکده پزشکی اصفهان, 2017
Background: The aim of this study was to compare the central corneal thickness measured by Orbscan II, ultrasound and Pentacam in patients undergoing photorefractive keratectomy (PRK).
Hassan Razmjoo, Shirin Fakhrizadeh
doaj  

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

THE ASSOCIATION OF CATARACT TYPE ON CENTRAL CORNEAL THICKNESS AFTER PHACOEMULSIFICATION CATARACT SURGERY

Pakistan Armed Forces Medical Journal, 2021
Objective: To assess any association between the type of cataract and the central corneal thickness at pre-operative and postoperative three-day and one-month appointments after phacoemulsification surgery. Study Design: Prospective, comparative study.
Hussnain Abbas, Abdul Rauf, Shagufta Perveen, Shahid Hamid Mehmood, Irshad Hussain, Khalid Naimat   +5 more
doaj  

Corneoscleral laceration and ocular burns caused by electronic cigarette explosions [PDF]

, 2016
PURPOSE: To report cases of acute globe rupture and bilateral corneal burns from electronic cigarette (EC) explosions. METHODS: Case series. RESULTS: We describe a series of patients with corneal injury caused by EC explosions.
Echalier, Elizabeth, Eck, Thomas W, Farooq, Asim V, Gregory, Darren G, Hong, Augustine R, Lubniewski, Anthony J, Paley, Grace L   +6 more
core   +2 more sources

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Elevated intraocular pressure in patients with acromegaly [PDF]

, 2014
To evaluate central corneal thickness (CCT) and intraocular pressure (IOP) in a cohort of acromegalic patients, and to correlate CCT with serum levels of growth hormone (GH) and insulin-like growth factor 1 (IGF-1)
Floriani, Irene, Giustina, Andrea, Katsanos, Andreas, Konstas, Anastasios, Mazziotti, Gherardo, Porcelli, Teresa, Quaranta, Luciano, Riva, Ivano   +7 more
core   +1 more source

MG53 Coordinates Macrophage Polarization and Neuroimmune Coupling to Promote Corneal Nerve Regeneration via the MPEG1–MVP–STAT6 Axis

Advanced Science, EarlyView.
Corneal nerve regeneration is critical to corneal wound healing processes. The current study reveals a novel role of MG53 in promoting corneal nerve regeneration after alkali induced injury. Mechanistically, MG53 enters macrophages via its receptor, MPEG1, promotes MVP K63 ubiquitination, and triggers STAT6 induced repair‐related genes expression ...
Peng Chen, Zhentao Zhang, Lilian Sakai, Yanping Xu, Luxi Zhang, Han Ye, William Sollenberger, Takahide Ikeda, Zhiyu Yan, Keerthika Sathish, Usman Alizai, Haitao Wen, Timothy M. Pawlik, Heather L. Chandler, Hua Zhu   +14 more
wiley   +1 more source

The frequency of non-pathologically thin corneas in young healthy adults

Clinical Ophthalmology, 2019
Hannah Rashdan, Manali Shah, Danielle M RobertsonDepartment of Ophthalmology, UT Southwestern Medical Center, Dallas, TX, USAPurpose: Measurement of normal corneal thickness and corneal epithelial thickness is important in keratorefractive surgery ...
Rashdan H, Shah M, Robertson DM
doaj