Results 151 to 160 of about 9,120,288 (390)

“A Leap into the Unknown”

open access: yesCentral Europe, 2019
This article provides insights into the creation of a website analyzing the responses to the Prague Spring designed by the students of East European Studies at the Ludwig Maximilian University of Munich and the University of Regensburg.
Fabian Riesinger, Verena Hesse
doaj  

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

open access: yesMolecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti   +3 more
wiley   +1 more source

Austrian High Enlightenment

open access: yesCentral Europe, 2019
This article examines state building under Joseph II in the Habsburg Empire between the period of 1780-1790 and considers the intellectual successes of Josephinism.
Joshkin Aziz Sezer
doaj  

Exchange Rate Regime and Wage Determination in Central and Eastern Europe [PDF]

open access: yes
After the eastern enlargement of the European Union due to increasing labor market integration, wage determination and monetary integration in Central and Eastern Europe have become key issues in European economic policy making. Based on the Scandinavian
Christina Ziegler, Gunther Schnabl
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Competitiveness Implications for Ireland of EU Enlargement [PDF]

open access: yes
Ten states, primarily from Central and Eastern Europe, are likely to be admitted to the EU within the next few years. The present paper assesses the competitiveness implications of this enlargement for Ireland.
Aoife Hannan   +3 more
core  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Russification and Russianization in Modern Historiography: Recent Developments and Future Directions

open access: yesCentral Europe
As the Soviet historical archives became accessible to Western scholars beginning in the 1980s, renewed scrutiny was placed on the imperial-colonial policies of the Russian Empire toward its borderlands.
Nicholas W. Sessums
doaj  

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