Results 61 to 70 of about 366,766 (262)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Bounds on the Closeness Centrality of a Graph

Bulletin of the Malaysian Mathematical Sciences Society
Abstract We present new values and bounds on the (normalised) closeness centrality $$\bar{\textsf{C}}_C$$ C ¯
Thomas Britz, Xin Hu, Abdellah Islam, Hopein C. Tang   +3 more
openaire   +3 more sources

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

A New Method for Centrality Measurement Using Generalized Fuzzy Graphs

Discrete Dynamics in Nature and Society, 2022
The fuzzy graph is the foundation of many actual structures such as networking, picture planning, and so on. Generalized fuzzy graphs (GFG) are ideal for avoiding certain constraints of fuzzy graphs.
R. Dhanalakshmi, Junaid Rashid, Jungeun Kim, Arun Kumar Sivaraman, Usman Naseem, Rajiv Vincent   +5 more
doaj   +1 more source

On decay centrality in graphs [PDF]

MATHEMATICA SCANDINAVICA, 2018
The decay centrality of a vertex $v$ in a graph $G$ with respect to a parameter $\delta \in (0,1)$ is a polynomial in δ such that for fixed $k$ the coefficient of $\delta ^k$ is equal to the number of vertices of $G$ at distance $k$ from $v$. This invariant (introduced independently by Jackson and Wolinsky in 1996 and Dangalchev in 2011) is considered ...
Coronicová Hurajová, Jana, Gago Álvarez, Silvia, Madaras, Tomas   +2 more
openaire   +3 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Graph Adaptive Attention Network with Cross-Entropy

Entropy
Non-Euclidean data, such as social networks and citation relationships between documents, have node and structural information. The Graph Convolutional Network (GCN) can automatically learn node features and association information between nodes.
Zhao Chen
doaj   +1 more source