Results 71 to 80 of about 366,766 (262)
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
On the Complexity of Stacked Graphs Associated with Paths and Cycles
AxiomsThe complexity of a graph, defined as its number of spanning trees, serves as a key measure of network reliability. Stacked graphs constitute a significant and versatile class of graphs, formed by superimposing multiple copies of a base graph upon a ...
Salama Nagy Daoud, Ahmad Asiri
doaj +1 more source
Central partition for a partition-distance and strong pattern graph
Revstat Statistical Journal, 2004 When several clustering algorithms are applied to a dataset E or the same algorithm with different parameters, we get several different partitions of the dataset.
Joaquim F. Pinto da Costa , P.R. Rao
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Scientific Knowledge Graph and Trend Analysis of Central Sensitization: A Bibliometric Analysis
Journal of Pain Research, 2022 Zhuo Li,1,2,* Chi Xu,2,* Jun Fu,2 Maimaiti Zulipikaer,2 Tao Deng,2 Jiying Chen2 1School of Medicine, Nankai University, Tianjin, People’s Republic of China; 2Department of Orthopedic Surgery, Chinese PLA General Hospital, Beijing, People’s ...
Li Z +5 more
doaj
Project centralization based on graph coloring
Proceedings of the 29th Annual ACM Symposium on Applied Computing, 2014 Version conflicts are common in a component-based system, where each component is developed and managed independently. Changes during the life-cycle of components require multiple versions to coexist. This creates a challenge in representing multiple versions for program analysis tools and execution platforms that are designed to handle only one ...
Ma, Lei, Artho, Cyrille, Sato, Hiroyuki
openaire +3 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
A graph theoretic analysis of leverage centrality
AKCE International Journal of Graphs and Combinatorics, 2017 13 ...
Roger Vargas Jr. +4 more
openaire +3 more sources
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source