Results 91 to 100 of about 366,766 (262)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Fractional Sturm-Liouville operators on compact star graphs
Demonstratio MathematicaIn this article, we examine two problems: a fractional Sturm-Liouville boundary value problem on a compact star graph and a fractional Sturm-Liouville transmission problem on a compact metric graph, where the orders αi{\alpha }_{i} of the fractional ...
Mutlu Gökhan, Uğurlu Ekin
doaj +1 more source
Circuits as Graphs: A Review of Graph Learning for Secure and Trustworthy Hardware
IEEE AccessModern Integrated Circuits (ICs) are highly interconnected, making graph representation a natural foundation for hardware security analysis. In recent years, graph-based approaches have gained significant traction in addressing a wide range of hardware ...
Afjal Hossan Sarower +2 more
doaj +1 more source
On centrally symmetric graphs [PDF]
Mathematica Bohemica, 1996 If \(L\) is a finite graded lattice with \(n\) atoms such that its dual lattice \(L^\star\) is strong and if its covering graph is centrally symmetric, then \(L\) is isomorphic to \(2^n\). This result is proved using a similar result of B. Zelinka which holds for a finite modular lattice with \(n\) atoms.
openaire +2 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Axiomatic characterization of the interval function of partial cubes and partial Hamming graphs
AKCE International Journal of Graphs and CombinatoricsInterval function of a graph is a well-known notion in metric graph theory and the axiomatic characterization using a set of first order axioms of different graph classes is an interesting problem in this area.
Jeny Jacob +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Accelerating knowledge graph and ontology engineering with large language models
Web SemanticsLarge Language Models bear the promise of significant acceleration of key Knowledge Graph and Ontology Engineering tasks, including ontology modeling, extension, modification, population, alignment, as well as entity disambiguation.
Cogan Shimizu, Pascal Hitzler
doaj +1 more source