Results 171 to 180 of about 50,114 (246)

Evaluation of the effectiveness and safety of anti‐CGRP monoclonal antibodies in patients with migraine and autoimmune diseases: IMMUNO‐CGRP study

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This study aimed to evaluate demographic characteristics, treatment effectiveness, and safety outcomes in patients with migraine undergoing anti‐calcitonin gene‐related peptide (CGRP) treatments regarding the presence of autoimmune diseases. Background CGRP has an important role in migraine pathophysiology through neuronal modulation
María Clara García‐Castillo   +37 more
wiley   +1 more source

Suzetrigine as a novel treatment for headache disorders: A case series

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Suzetrigine is a selective voltage‐gated sodium channel blocker that was recently approved by the US Food and Drug Administration for the treatment of acute pain. We retrospectively evaluated the efficacy and tolerability of suzetrigine for the treatment of different headache disorders in patients refractory to standard treatments in an ...
Molly Fensterwald   +15 more
wiley   +1 more source

Iron Overload: Pathophysiology, Diagnosis and Monitoring

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Iron overload is associated with significant health risks, underscoring the importance of understanding its pathophysiology as well as establishing accurate diagnostic and monitoring methods. Chronic iron overload is associated with either genetic disorders characterized by excessive iron accumulation (hereditary hemochromatosis), or is ...
Elena Chatzikalil   +3 more
wiley   +1 more source

Novel Clinical and Histological Insights into Cutaneous Kikuchi‐Fujimoto Disease and Kikuchi Disease‐Like Inflammatory Pattern (KLIP)

open access: yes
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Magí Brufau‐Cochs   +7 more
wiley   +1 more source

Functional immune profiling reveals CD4+ T cell dysregulation in coeliac disease

open access: yesImmunology &Cell Biology, EarlyView.
The T cell momentum assay quantifies division, survival and activation decay to reveal intrinsic CD4+ programming defects marked by prolonged activation and impaired feedback control in coeliac disease. This scalable platform provides a functional screen for early T cell dysregulation across autoimmune and immune‐mediated diseases.
Anthony J Farchione   +13 more
wiley   +1 more source

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