Hypogonadotropic Hypogonadism Revisited [PDF]
Clinics, 2013 Impaired testicular function, i.e., hypogonadism, can result from a primary testicular disorder (hypergonadotropic) or occur secondary to hypothalamic-pituitary dysfunction (hypogonadotropic).
Sandro C. Esteves, Renato Fraietta
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Genetics of Idiopathic Hypogonadotropic Hypogonadism [PDF]
JCRPEIdiopathic hypogonadotropic hypogonadism (IHH) comprises a group of disorders characterized by deficient secretion or action of gonadotropin-releasing hormone (GnRH), leading to impaired pubertal development and infertility.
A. Kemal Topaloğlu, Leman Damla Kotan
doaj +4 more sources
Treatment of congenital hypogonadotropic hypogonadism in male patients [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2022 Congenital hypogonadotropic hypogonadism (CHH) is characterized by complete or partial failure of pubertal development because of inadequate secretion of gonadotropic hormones.
Hae Sang Lee +2 more
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Pituitary imaging findings in pediatric patients with idiopathic hypogonadotropic hypogonadism
Endocrine Regulations, 2023 Objective. Idiopathic hypogonadotropic hypogonadism in children is a disease leading to a puberty absence. Some hypothalamic and pituitary defects cause hypogonadotropic hypogonadism.
Bitkin Eda Celebi +2 more
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Male hypogonadotropic hypogonadism in various genetic disorders [PDF]
Journal of Education, Health and Sport, 2020 Introduction and purpose: Male hypogonadism is diagnosed in patients with total testosterone under 9-12nmol/L (250-350ng/dl) in serum which is associated with numerous symptoms which can severely lower the quality of patients life.
Sylwiusz Niedobylski +6 more
doaj +2 more sources
Unraveling Delayed Puberty: A Rare Case of Congenital Hypogonadotropic Hypogonadism Masked by Celiac Disease and Plummer–Vinson Syndrome [PDF]
Clinical Case ReportsCongenital hypogonadotropic hypogonadism (CHH) is a rare disorder that results in delayed puberty and infertility due to impaired secretion of gonadotropin‐releasing hormone (GnRH).
Osama Ahmad +7 more
doaj +2 more sources
Management of infertility in women with hypothalamic hypogonadotropic hypogonadism: an expert opinion [PDF]
Reproductive Biology and EndocrinologyBackground Hypothalamic gonadotropin-releasing hormone (GnRH) plays a central role in regulating the pituitary-gonadal axis. The pulsatility of GnRH release is critical for maintaining the function of GnRH receptors and the secretion pattern of ...
Geoffroy Robin +6 more
doaj +2 more sources
Frequency of the allelic variant (Trp8Arg/Ile15Thr) of the luteinizing hormone gene in a Brazilian cohort of healthy subjects and in patients with hypogonadotropic hypogonadism [PDF]
Clinics, 2005 PURPOSE: To evaluate the frequency of allelic variant Trp8Arg/Ile15Thr in the luteinizing hormone beta-subunit gene in a Brazilian population of healthy subjects and in patients with hypogonadotropic hypogonadism.
Karina Berger +5 more
doaj +1 more source
A novel mutation in RNF216 gene in a Turkish case with Gordon Holmes syndrome
BMC Medical Genomics, 2023 Background Gordon Holmes syndrome (GHS) is a rare autosomal recessive disorder characterized by hypogonadotropic hypogonadism, cognitive decline, and cerebellar ataxia.
Nazlı Durmaz Çelik +6 more
doaj +1 more source
New findings in oligogenic inheritance of congenital hypogonadotropic hypogonadism
Archives of Medical Science, 2020 Introduction Congenital hypogonadotropic hypogonadism results from a dysfunction of the hypothalamic-pituitary-gonadal axis, which is essential for the development and function of the reproductive system. It may be associated with anosmia, referred to as
Agnieszka Gach +13 more
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