Results 21 to 30 of about 23,463 (198)
Gonadotropins in hypogonadotropic hypogonadism in adolescents: prospects of treatment
Лечащий Врач, 2021 Analytical review of modern technologies of hypogonadotropic hypogonadism therapy in adolescents was presented, using recombinant gonadotropins, currently recognized as an effective remedy of puberty induction and substitutive hormone therapy in the ...
Yu. L. Skorodok +3 more
doaj +1 more source
Personality Development of Adolescents with Hypogonadotropic Hypogonadism
Psychological Reports, 1996 Hypogonadotropic hypogonadism is a disorder of puberty characterized by absence of spontaneous sexual maturation. 8 male adolescents with this disorder, who were treated with pulsatile GnRH administration, were examined psychologically by means of standardized interviews.
Huisman, J. +2 more
openaire +4 more sources
Genetics of hypogonadotropic hypogonadism [PDF]
Translational Andrology and Urology, 2021 Male congenital hypogonadotropic hypogonadism (CHH) is a heterogenous group of genetic disorders that cause impairment in the production or action of gonadotropin releasing hormone (GnRH). These defects result in dysfunction of the hypothalamic-pituitary-gonadal hormone axis, leading to low testosterone levels and impaired fertility.
Millar, Adam C. +2 more
openaire +2 more sources
The Spectrum of Congenital Hypogonadotropic Hypogonadism: A 30-Year Experience at a Tertiary Paediatric Centre. [PDF]
Clin Endocrinol (Oxf)ABSTRACT Congenital hypogonadotropic hypogonadism (CHH) is a rare group of disorders of gonadotropin deficiency, either isolated or as a part of multiple pituitary hormone deficiencies (MPHD). We aimed to describe the spectrum of presentation, diagnosis, and management practices of CHH spanning 30 years at an Australian tertiary paediatric centre. This
Kook M, McGee RG, Ambler G, Cho YH.
europepmc +2 more sources
Hypogonadotropic Hypogonadism Before and After Transsphenoidal Surgery for Non-Functioning Pituitary Adenoma. [PDF]
Clin Endocrinol (Oxf)ABSTRACT Objective The effect of transsphenoidal surgery (TSS) on the hypothalamic‐pituitary‐gonadal (HPG) axis in patients with non‐functioning pituitary adenomas (NFPA) is underexplored, especially in women. Our aim was to investigate the HPG axis function before and after TSS, its association with quality of life (QoL), and to identify factors that ...
Hantelius V +6 more
europepmc +2 more sources
Neuroradiological findings in hypogonadotropic hypogonadism.
Minerva endocrinologica, 2016 Hypogonadotropic hypogonadism (HH) is a clinical hallmark of a heterogeneous group of acquired and inherited diseases. Patients with HH undergo brain imaging in order to investigate morphological or signal abnormalities at the level of the hypothalamic-pituitary structures.
Salvalaggio A., Elefante A., Manara R
openaire +4 more sources
Boosting Male Fertility: The Impact of Gonadotropin Therapy on Hypogonadotropic Hypogonadism-A Systematic Review and Meta-Analysis. [PDF]
AndrologyABSTRACT Background Male hypogonadotropic hypogonadism typically presents with azoospermia and is one of the few causes of infertility amenable to a medical intervention. Gonadotropin therapy offers a chance to restore spermatogenesis and fertility in these individuals.
Huijben M +3 more
europepmc +2 more sources
The Genetic Backdrop of Hypogonadotropic Hypogonadism [PDF]
International Journal of Molecular Sciences, 2021 The pituitary is an organ of dual provenance: the anterior lobe is epithelial in origin, whereas the posterior lobe derives from the neural ectoderm. The pituitary gland is a pivotal element of the axis regulating reproductive function in mammals. It collects signals from the hypothalamus, and by secreting gonadotropins (FSH and LH) it stimulates the ...
Anna Szeliga +8 more
openaire +2 more sources
Reversal of Congenital Hypogonadotropic Hypogonadism. [PDF]
J Clin Endocrinol MetabAbstract Context Congenital genetic disorders have been traditionally considered to be lifelong. An exception to this long-held view is the reversal of congenital hypogonadotropic hypogonadism (CHH).
Dwyer AA, Stamou M.
europepmc +4 more sources
Normosmic idiopathic hypogonadotropic hypogonadism due to a novel GNRH1 variant in two siblings
Endocrinology, Diabetes & Metabolism Case Reports, 2020 Hypogonadotropic hypogonadism is characterised by insufficient secretion of pituitary gonadotropins resulting in delayed puberty, anovulation and azoospermia. When hypogonadotropic hypogonadism occurs in the absence of structural or functional lesions of
Satyanarayana V Sagi +9 more
doaj +1 more source