Results 201 to 210 of about 6,594,395 (276)

Voltage‐gated potassium channels mediate thyroid hormone control of skeletal muscle excitability

The Journal of Physiology, EarlyView.
Abstract figure legend Thyroid hormone (TH)‐dependent remodelling of potassium (K+) channel networks regulates skeletal muscle (SkM) excitability. Triiodothyronine (T3), locally generated from thyroxine (T4) by type 2 deiodinase (D2), binds thyroid hormone receptors (TRα/β) and modulates transcription via thyroid response elements (TREs).
Annarita Nappi, Caterina Miro, Annunziata Gaetana Cicatiello, Ilaria Piccialli, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Rosa Sirica, Melania Murolo, Emery Di Cicco, Daniela Terracciano, Anna Pannaccione, Monica Dentice   +12 more
wiley   +1 more source

KV channels contribute to thermal hyperaemia in skeletal muscle of humans

The Journal of Physiology, EarlyView.
Abstract figure legend Using skeletal muscle microdialysis and pulsed short‐wave diathermy, we examined the contribution of KV channels to thermal hyperaemia in human skeletal muscle. KV channel antagonism with 4‐aminopyridine attenuated thermal hyperaemia by ∼65%, identifying a critical downstream role for these ion channels in the vasodilatory ...
Ysabella I. Ruiz‐Pick, Sophia G. Wagle‐Babb, Asim Kichloo, Albert H. Olivencia‐Yurvati, Gregory M. Dick, Steven A. Romero   +5 more
wiley   +1 more source

Painless thyroiditis associated with SARS-CoV-2 and influenza infections in a patient with central hypothyroidism after pituitary surgery. [PDF]

Endocrinol Diabetes Metab Case Rep
Wada N, Sugawara H, Satoh A, Baba S, Miyoshi A, Obara S.   +5 more
europepmc   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, Volume 30, Issue 6, Page 908-924, December 2026.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Metabolomics Reveals Multiple Metabolic Alterations and Biomarkers of Disease Severity in Facioscapulohumeral Muscle Dystrophy

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 6, December 2026.
ABSTRACT Background Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is one of the most common adult‐onset myopathies and is causally associated with a contraction of the D4Z4 macrosatellite repeat array on chromosome 4. It presents with a variable pattern of progressive muscle weakness affecting the face, shoulder girdle and lower limbs ...
Pascal Reynier, Mathieu Michel, Patrick Vandeputte, Noemi Albano, Dario Zoppi, Charlène Gillet, Sara Pini, Andi Nuredini, Martina De Maria, Odile Blanchet, Naig Gueguen, Juan Manuel Chao de la Barca, Lucia Ruggiero, Rossella Tupler, Marco Spinazzi   +14 more
wiley   +1 more source

Heat Perceptions, Behaviors, and Barriers of Unhoused Individuals in Germany

Public Health Challenges, Volume 5, Issue 4, December 2026.
Across in‐depth interviews and a survey of 252 unhoused people in 13 German cities, many underestimated heat risks yet often experienced heat‐related fatigue, nausea, or faintness. Participants reported limited hydration and frequent eviction from cooling spots, heat‐aggravating medication whose dosage and storage were rarely adapted, and minimal sun ...
Philipp Sprengholz, Robert W. Bruckmann, Linnea Noomi Daniel, Elisabeth Luna Else, Lilliana Babette Moreth, Nicole Piatti   +5 more
wiley   +1 more source

Prevalence and Associated Factors of Thyroid Dysfunction Among Clinical Populations in Bangladesh: A Systematic Review and Meta‐Analysis

Public Health Challenges, Volume 5, Issue 4, December 2026.
This systematic review and meta‐analysis of Bangladeshi clinical populations found that nearly one‐quarter (23.72%) had thyroid dysfunction, predominantly hypothyroidism. Patients with metabolic‐inflammatory disorders showed markedly higher prevalence (34.77%) than endocrine‐reproductive groups (19.14%), highlighting a “dual burden” of endocrine and ...
Most. Rubaia Akter Rifat, Md. Raiyan Hasan Nabid, Md. Tanjim, Nourin Sultana, Md. Moin Uddin Riyad, Md. Kaderi Kibria   +5 more
wiley   +1 more source

Long‐Term Determinants of Lean Mass in Ageing Adults: A 17‐Year Longitudinal Cohort Study With Repeated Measures

Australasian Journal on Ageing, Volume 45, Issue 4, December 2026.
ABSTRACT Objective Age‐related loss of lean mass is a hallmark of sarcopenia and a contributor to functional decline and morbidity in ageing populations. This study aimed to identify long‐term determinants of lean mass during ageing. Methods Data from 3033 participants (ages 20–96 years; 49% women) in the Geelong Osteoporosis Study were analysed using ...
Aminu Suleiman, Mojtaba Lotfaliany, Lana J. Williams, Kara B. Anderson, Emma C. West, Amanda L. Stuart, Julie A. Pasco   +6 more
wiley   +1 more source