Results 141 to 150 of about 3,972,008 (302)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Open Citations - Indexing PubMed Central OA data
, 2013 As part of our work on the Open Citations extensions project, I have recently been doing one of my favourite things – namely indexing large quantities of data then exploring it. On this project we are interested in the PubMed Central Open Access subset, and more specifically, we are interested in what we can do … Continue reading Open Citations ...
openaire +3 more sources
Research Reports in Clinical Cardiology, 2012 Anatoliy N Rogoza,1 Aleksandr A Kuznetsov21Cardiology Research Complex, Moscow, Russian Federation; 2Therapy Research Institute, Siberian branch of Russian Academy of Medical Science, Novosibirsk, Russian FederationIntroduction: The aim of this study is ...
Rogoza AN, Kuznetsov AA
doaj
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
P3.08 NITROGLYCERIN EFFECT ON AORTAL AUGMENTATION AND CENTRAL AUGMENTATION INDEX
Artery Research, 2011 M. Berzina +5 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Computing Some Topological Indices of Two Kinds of Dendrimer Graphs Gn and Hn
Journal of MathematicsDendrimer molecules are macromolecules which have many applications in nanosciences, drug delivery, biology, and different areas of sciences. Topological indices of chemical graph theory are numerical descriptor of a molecular structure.
Hojat Kaviani, Lotfallah Pourfaraj
doaj +1 more source
The Consequences of Inequality: A New Measure of Human Development [PDF]
Marking the 20th anniversary of the Human Development Index (HDI), the United Nations Development Programme (UNDP) has published a revised measure that also accounts for inequality (IHDI).
Guo Xu, Veronika Hümmer
core
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source