Results 61 to 70 of about 6,832,738 (209)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Acleris lorquiniana (Lepidoptera: Tortricidae), in Central Italy

open access: yesJournal of Entomological and Acarological Research, 2013
Acleris lorquiniana (Duponchel, 1835) is a Palaearctic species that is known from Central and Northern Europe. This species was mentioned as occurring in Italy, but no precise collecting data were provided. The presence of Marsh button, A.
M. Pinzari, M. Pinzari
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Paleoseismology of silent faults in the Central Apennines (Italy): the Campo Imperatore Fault (Gran Sasso Range Fault System)

open access: yesAnnals of Geophysics, 2003
Paleoseismological analyses were performed along the Campo Imperatore Fault (part of the Gran Sasso Range Fault System) in order to define the seismogenic behaviour (recurrence interval for surface faulting events, elapsed time since the last ...
M. Moro, P. Galli, F. Galadini
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Obesity and Skin Carotenoid Score in Children from Center–Southern Italian Regions

open access: yesAntioxidants
Childhood obesity represents a public concern worldwide. Evidence indicates that fruits and vegetables (FV) consumed as part of the daily diet reduce the global burden of obesity.
Giuseppina Augimeri   +7 more
doaj   +1 more source

Paleoseismology of silent faults in the Central Apennines (Italy): the Mt. Vettore and Laga Mts. Faults

open access: yesAnnals of Geophysics, 2003
Paleoseismological analyses have been performed in the Central Apennines along faults showing geomorphological evidence of Late Quaternary activity and characterised by the absence of historical seismicity. Three trenches were made along the Mt.
P. Galli, F. Galadini
doaj   +1 more source

Central Connections Fall 2015 [PDF]

open access: yes, 2015
Central connections was the free magazine for Central Washington University alumni and friends. In 2019 it was replaced by Crimson and Black.https://digitalcommons.cwu.edu/central_connections/1002/thumbnail ...
Central Washington University
core   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

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