Results 71 to 80 of about 481,762 (313)

Active faulting along the Mt. Morrone South Western slope (Central Appennines, Central Italy)

open access: yes, 2007
Active faulting along the Mt. Morrone South Western slope (Central Appennines, Central Italy)PublishedRimini3.10.
Giaccio, B.   +6 more
core   +1 more source

Hydrochemical determination of source water contributions to Lake Lungo and Lake Ripasottile (central Italy)

open access: yesJournal of Limnology, 2016
Lake Lungo and Lake Ripasottile are two shallow (4-5 m) lakes located in the Rieti Basin, central Italy, that have been described previously as surface outcroppings of the groundwater table.
Claire Archer   +8 more
doaj   +1 more source

Carbon isotopic data of Hauterivian carbonate samples obtained from Fiume Bosso section, central Italy

open access: yes, 2021
Data sets include the osmium and carbon isotopic information of the limestone samples collected from the Fiume Bosso section (43°31'07.2N 12°34'15.4E), central Italy.
Matsumoto, Hironao   +3 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Molecular Epidemiological Insights into Colistin-Resistant and Carbapenemases-Producing Clinical Klebsiella pneumoniae Isolates

open access: yesInfection and Drug Resistance, 2019
Domiziana Di Tella, Manuela Tamburro, Giuliana Guerrizio, Incoronata Fanelli, Michela Lucia Sammarco, Giancarlo Ripabelli Department of Medicine and Health Sciences “Vincenzo Tiberio”, University of Molise, Campobasso, ItalyCorrespondence ...
Di Tella D   +5 more
doaj  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Osmium isotopic data of Hauterivian carbonate samples obtained from Fiume Bosso section, central Italy

open access: yes, 2021
Data sets include the osmium and carbon isotopic information of the limestone samples collected from the Fiume Bosso section (43°31'07.2N 12°34'15.4E), central Italy.
Matsumoto, Hironao   +3 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Leishmania infantum and Dirofilaria immitis infections in Italy, 2009–2019: changing distribution patterns

open access: yesParasites & Vectors, 2020
Background For long time, canine leishmaniosis (CanL) was considered endemic in the southern, central, and insular regions of Italy, whereas heartworm disease (HW) caused by Dirofilaria immitis was considered endemic in the northern region and in the ...
Jairo Mendoza-Roldan   +7 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

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