Results 41 to 50 of about 17,919,985 (298)

Bridging the gap: introduction of an antimicrobial peripherally inserted central catheter (PICC) in response to high PICC central line-associated bloodstream infection incidence

, 2021
OBJECTIVE: To reduce the incidence of central line-associated bloodstream infection (CLABSI) in peripherally inserted central catheters (PICC) through the introduction of an antimicrobial (AM) catheter as recommended in evidence-based guidelines and ...
Sleweon, Thomas, DeVries, Michelle
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Impact of International Nosocomial Infection Control Consortium's multidimensional approach on central line-associated bloodstream infection rates in Bahrain

, 2020
Central line-associated bloodstream infections are serious life-threatening infections in the intensive care unit setting. To analyze the impact of the International Nosocomial Infection Control Consortium (INICC) Multidimensional Approach (IMA) and ...
Alkhawaja, Safaa, Saeed, Nermeen Kamal, Abdul-Aziz, Sana, Humood, Zainab Mahdi, Alsayegh, Ameena, Rosenthal, Victor Daniel, Magray, Tahira Anwar Saeed, Ali, Khadija Mohamed, Swar, Saleh   +8 more
core   +1 more source

Excess length of stay due to central line–associated bloodstream infection in intensive care units in Argentina, Brazil, and Mexico [PDF]

, 2010
Objective.To estimate the excess length of stay in an intensive care unit (ICU) due to a central line–associated bloodstream infection (CLABSI), using a multistate model that accounts for the timing of infection.\ud \ud Design.A cohort of 3,560 patients ...
Barnett, Adrian G., Victor D. Rosenthal, Reinaldo Salomao, Nicholas Graves, Rangel‐Frausto, Manuel Sigfrido, Sigfrido Rangel-Frausto, Manuel, Salomao, Reinaldo, Graves, Nicholas, Rosenthal, Victor D., Adrian G. Barnett, Manuel Sigfrido Rangel-Frausto   +10 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Pattern of bacterial bloodstream infections in hemodialysis patients

Journal of Infection in Developing Countries
Introduction: Bloodstream infection (BSI) is a major contributor to morbidity and mortality in hemodialysis patients. Our objective was to identify pathogens causing BSI, its incidence, and associated risk factors.
Qurat Ul Ain, Muhammad N Hashmi, Alaa AL Sayed, Hammad Raza, Muhammad A Khan, Ebtehaj Alahmari, Raghad Alajlan, Reham Eladrosi, Muhammad W Saeed, Abdallah Ibrahim, Fayez Hejaili   +10 more
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Prevention of central venous line associated bloodstream infections in adult intensive care units: A systematic review

, 2017
Background In adult Intensive Care Units, the complexity of patient treatment requirements make the use of central venous lines essential. Despite the potential benefits central venous lines can have for patients, there is a high risk of bloodstream ...
Diana Carolina Velasquez Reyes, Julia Morphet, Bloomer, Melissa, Morphet, Julia, Melissa Bloomer, Reyes, Diana Carolina Velasquez   +5 more
core   +1 more source

Analyzing central-line associated bloodstream infection prevention bundles in 22 countries: The results of ID-IRI survey [PDF]

, 2022
Background: Because central line-associated bloodstream infections (CLABSIs) are a significant complication of central venous access, it is critical to prevent CLABSIs through the use of central line bundles.
Amer, Fatma, Erdem, Hakan, Devrim, Ilker, El-Kholy, Amani, Almohaizeie, Abdullah, Rahimi, Bilal Ahmad, Logar, Mateja   +6 more
core   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists in Multiple Sclerosis: A Topical Narrative Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are a relatively new class of drugs that were initially approved by the US Food and Drug Administration to improve glycemic control in patients with type 2 diabetes mellitus and, subsequently, weight reduction in patients with obesity.
Audrey Y. Chang, Farrah J. Mateen
wiley   +1 more source