Results 111 to 120 of about 4,073,542 (303)

Equivariant Alperin-Robinson's Conjecture reduces to almost-simple k*-groups [PDF]

open access: yes, 2012
In a recent paper, Gabriel Navarro and Pham Huu Tiep show that the so-called Alperin Weight Conjecture can be verified via the Classification of the Finite Simple Groups, provided any simple group fulfills a very precise list of conditions.
Puig, Lluis
core  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Friedrich List: un profeta olvidado

open access: yesEconómica, 1969
Los estudiosos de la historia del pensamiento económico han subvaluado la contribución de Friedrich List al desarrollo de nuestra ciencia. Esta es una afirmación muy fuerte, y parecería más adecuado incluirla bajo "comentario final" y no en la sección ...
Arturo C. Meyer
doaj  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

An Arrow-type result for inferring a species tree from gene trees [PDF]

open access: yes, 2013
The reconstruction of a central tendency `species tree' from a large number of conflicting gene trees is a central problem in systematic biology. Moreover, it becomes particularly problematic when taxon coverage is patchy, so that not all taxa are ...
Steel, Mike
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Employee compensation management: The case of the national minimum wage in Nigeria

open access: yesJournal of Human Resource Management, 2016
This article examines the issue of employee compensation in Nigeria with particular reference to the National minimum Wage. The paper notes that proper employee compensation management is central to industrial harmony in all organizations.
Samuel O. Oyedele
doaj  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Classification of Ten-Dimensional Heterotic Strings

open access: yes, 1991
Progress towards the classification of the meromorphic $c=24$ conformal field theories is reported. It is shown if such a theory has any spin-1 currents, it is either the Leech lattice CFT, or it can be written as a tensor product of Kac-Moody algebras ...
Schellekens, A. N.
core   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

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