Results 161 to 170 of about 3,963,986 (357)
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Interstates Cooperation for Irrigation of Amu Darya River Banks, Its Potential Role as a Solution for the Poppy Problem [PDF]
Depletion of water resources requires us to search for non-conventional strategies for water preservation and irrigation. Sustainable management of such water resources along with the development of sustainable irrigation systems will contribute to the ...
Nader Ghotbi, Tsuneo Tsukatani
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The effect of deforestation rate on land tenure in Central Africa [PDF]
The CoForTips project aims at the promotion of better management of the forest of the Congo Basin by presenting to the policy makers plausible scenarios of social and ecological systems evolution.
Codina Llavina, Elisabet +4 more
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Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Transferring Rhineland Capitalism to the Polish-German Border: Perceptions of Bank Governance and Practice in Zgorzelec-Görlitz [PDF]
This article looks at the past development and potential of the Rhenish capitalist model. We discuss the origins and nature of the model and the model in crisis.
Bernardo Batiz-Lazo +2 more
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Storing carbon in soil. Can we slow a revolving door? [PDF]
There is no doubt that soils are a vast store of carbon and partially control the carbon dioxide content of the atmosphere. Maintaining soil organic matter is also crucial for production and environmental protection.
Schipper, Louis A.
core +1 more source
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
At a time when many companies are under pressure to reduce "times-to-market" the management of product information from the early stages of design through assembly to manufacture and production has become increasingly important.
Baker, N. +12 more
core +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
The evolution of central banking [PDF]
Institutions known as central banks emerged or were established as commercial banks or government banks. Their evolution into central banks came with their monopoly issuing notes and their role as lender of last resort, among other functions.
Capie, Forrest
core

