Results 131 to 140 of about 6,859,440 (291)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
On the moments of Hecke series at central points
Functiones et Approximatio Commentarii Mathematici, 2002 Asymptotic formulas for $\sum_{κ_j\le K}α_j H_j^k(1/2)$ are proved when $k = 3,4$, where $H_j(s)$ is the Hecke series.
openaire +4 more sources
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Moments of the unbalanced non-central chi-square distribution
The unbalanced non-central chi-square distribution with 1 degree of freedom, introduced (and called weighted non-central chi-square distribution) by Chen is generalized to the case of [nu] degrees of freedom.
Grau, Daniel
core
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
On Limiting Distributions Of Estimation Of Central Moments
, 2008 This paper has been withdrawn at the author's request.
openaire +2 more sources
Magnetic Moments in Central Europe 2022
Croatica chemica acta, 2022 The eight international conference Magnetic Moments in Central Europe (MMCE) took place from 1 to 4 June 2022 at the Congress centre of the hotel Zora in Primošten, Croatia. The Conference was organized by Croatian Chemical Society and Department of Chemistry, Faculty of Science, University of Zagreb.
openaire +2 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Approximation by q-Post-Widder Operators Based on a New Parameter
Abstract and Applied AnalysisThe purpose of this paper is to introduce q-Post–Widder operators based on a new parameter and study their approximation properties. The moments and central moments are investigated.
Qiu Lin
doaj +1 more source