ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic +6 more
wiley +1 more source
Astrocytes play a pivotal role in the inflammatory response triggered by traumatic brain injury (TBI). They are not only involved in the initial inflammatory response following injury but also significantly contribute to Astrocyte activation and ...
Haifeng Zhang +10 more
doaj +1 more source
Occupational Risk Factors Associated with Perceived Central Nervous System Disorder among Printing Industry Workers In Medan [PDF]
Background: Toluene is a colorless, water-insoluble liquid, aromatic hydro-carbon, with the smell associated with paint thinners. Toluene is used in the printing of colored illustrations in media such as catalogues and magazines.
Ashar, T. (Taufik ) +2 more
core
The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis
ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen +5 more
wiley +1 more source
Prophylactic Management of Vestibular Migraine: A Systematic Review
ABSTRACT Background Vestibular migraine (VM) is a neurological disorder characterized by episodic vertigo in patients with migraine, contributing to substantial functional impairment. Although VM is relatively common, a consensus on effective prophylactic treatments is lacking.
Hussain Ali Almohammed +11 more
wiley +1 more source
Pleomorphic xanthoastrocytoma with anaplastic features: one case report and review of literature
Objective To investigate the clinicopathological features of pleomorphic xanthoastrocytoma with anaplastic features (PXA-A). Methods The clinical manifestations, imaging, histopathological features, and immunophenotype were analyzed in one case of ...
Cui-yun SUN, Shi-zhu YU
doaj
Integration of visual stimuli by the crayfish central nervous system [PDF]
For the crayfish, properties of visually reacting interneurone types in the optic nerve are described on the basis of single-unit analysis. Sustaining fibres show: (a) ‘surround’ inhibition over the whole retina, including the excitatory field; (b) ‘on’
Wiersma, C. A. G., Yamaguchi, T.
core
Autologous, Gene-Modified Hematopoietic Stem and Progenitor Cells Repopulate the Central Nervous System with Distinct Clonal Variants [PDF]
Christopher W. Peterson +14 more
openalex +1 more source
Lessons Learned: Quality Analysis of Optical Coherence Tomography in Neuromyelitis Optica
ABSTRACT Introduction Optical coherence tomography (OCT)‐derived retina measurements are markers for neuroaxonal visual pathway status. High‐quality OCT scans are essential for reliable measurements, but their acquisition is particularly challenging in eyes with severe visual impairment, as often observed in neuromyelitis optica spectrum disorders ...
Hadi Salih +40 more
wiley +1 more source
Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan +22 more
wiley +1 more source

