Results 151 to 160 of about 1,988,517 (312)

Analysis of Central Nervous System Factors and Muscle Hypertrophic Factors in a Muscle Strengthening Exercise: Changes in Muscle Thickness and a Discrete Wavelet Transform in Surface Electromyogram Analysis at Maximum Muscle Strength

, 2021
Kazunori Morozumi, Katsuyuki Morishita, Yuka Yokoi, Katsuhiro Furukawa, Hiroto Sasaki, Tetsuro Watanabe   +5 more
openalex   +2 more sources

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source

Persistent Leukoencephalopathy Following H1N1 Infection Associated With a Novel MYRF Variant (p.Gly735Asp)

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Mutations in myelin regulatory factor (MYRF) are linked to demyelinating disorders. We report a 38‐year‐old male who developed acute symmetric leukoencephalopathy mimicking a stroke following an influenza A virus infection. While clinical symptoms markedly improved with corticosteroids, MRI revealed persistent white matter lesions, contrasting
Jinghan Hu, Leiyun Huang, Wan Zhu, Min Peng, Qiang Gong, Jing Qian   +5 more
wiley   +1 more source

A novel protein SPECC1-415aa encoded by N6-methyladenosine modified circSPECC1 regulates the sensitivity of glioblastoma to TMZ

Cellular & Molecular Biology Letters
Background Circular RNAs (circRNAs) can influence a variety of biological functions and act as a significant role in the progression and recurrence of glioblastoma (GBM).
Cheng Wei, Dazhao Peng, Boyuan Jing, Bo Wang, Zesheng Li, Runze Yu, Shu Zhang, Jinquan Cai, Zhenyu Zhang, Jianning Zhang, Lei Han   +10 more
doaj   +1 more source

Leveraging the dynamic blood–brain barrier for central nervous system nanoparticle-based drug delivery applications

, 2020
Connor Copeland, Sarah E. Stabenfeldt
openalex   +2 more sources

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

An examination of Wuhan City healthcare personnel afflicted with SARS-CoV-2 Omicron variants between December 15, 2022, and January 5, 2023, during the rapid Omicron outbreak in China

Journal of Infection in Developing Countries, 2023
Yingyu He, Yuan Huang, Fang Zhang, Shangen Zheng, Wanbing Liu, Lei Liu   +5 more
doaj   +1 more source

A Case of Histoplasmosis with Central Nervous System Relapse after Itraconazole Therapy Needs Further Research [PDF]

, 2020
Prashanth Peddi, Tejo Challa, Sreenath Meegada, Madhavi Annakula, Evan Mar   +4 more
openalex   +1 more source

Multi‐Omics Integration for Advancing Glioma Precision Medicine

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas are among the most malignant and aggressive tumors of the central nervous system, characterized by the absence of early diagnostic markers, poor prognosis, and a lack of effective treatments. Advances in high‐throughput technologies have facilitated a refined molecular classification of gliomas, incorporating genetic features. However,
Maria Guarnaccia, Valentina La Cognata, Giulia Gentile, Giovanna Morello, Sebastiano Cavallaro   +4 more
wiley   +1 more source

The Case of a 28‐Year‐Old Woman With Medically Refractory Focal Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We present the case of a 28‐year‐old right‐handed woman with medically refractory focal epilepsy. Her seizure semiology and electroencephalography (EEG) indicated a seizure onset zone in the right central‐parietal area. However, both MRI and PET scans were unremarkable, showing no focal lesions or areas of altered metabolism.
Rishi Sharma, Ilo Leppik, Thomas Henry, Thaddeus Walczak, Sima Patel, Robert McGovern   +5 more
wiley   +1 more source