Results 191 to 200 of about 3,233,933 (403)

A novel protein SPECC1-415aa encoded by N6-methyladenosine modified circSPECC1 regulates the sensitivity of glioblastoma to TMZ

Cellular & Molecular Biology Letters
Background Circular RNAs (circRNAs) can influence a variety of biological functions and act as a significant role in the progression and recurrence of glioblastoma (GBM).
Cheng Wei, Dazhao Peng, Boyuan Jing, Bo Wang, Zesheng Li, Runze Yu, Shu Zhang, Jinquan Cai, Zhenyu Zhang, Jianning Zhang, Lei Han   +10 more
doaj   +1 more source

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins.

Proceedings of the National Academy of Sciences of the United States of America, 1998
M. Lambert, A. Barlow, B. Chromy, C. Edwards, R. Freed, M. Liosatos, Todd E. Morgan, I. Rozovsky, B. Trommer, K. Viola, P. Wals, Zhang Chi, C. Finch, G. Krafft, W. Klein   +14 more
semanticscholar   +1 more source

Central Nervous System Cancers [PDF]

Journal of the National Comprehensive Cancer Network, 2011
Steven S, Brem, Philip J, Bierman, Henry, Brem, Nicholas, Butowski, Marc C, Chamberlain, Ennio A, Chiocca, Lisa M, DeAngelis, Robert A, Fenstermaker, Allan, Friedman, Mark R, Gilbert, Deneen, Hesser, Larry, Junck, Gerald P, Linette, Jay S, Loeffler, Moshe H, Maor, Madison, Michael, Paul L, Moots, Tara, Morrison, Maciej, Mrugala, Louis Burt, Nabors, Herbert B, Newton, Jana, Portnow, Jeffrey J, Raizer, Lawrence, Recht, Dennis C, Shrieve, Allen K, Sills, Frank D, Vrionis, Patrick Y, Wen   +27 more
openaire   +2 more sources

Fibrinogen Changes Before and After Intravenous Thrombolysis as Predictors of Cerebral Injury and Clinical Outcomes in Acute Ischemic Stroke: A Multicenter Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma fibrinogen is essential in thrombosis and fibrinolysis, yet its dynamic changes pre‐ and post‐intravenous thrombolysis (IVT) for predicting brain injury severity and prognosis in acute ischemic stroke (AIS) patients remain unclear.
Wenhai Zhai, Yang Qu, Reziya Abuduxukuer, Kejia Zhang, Peng Zhang, Xin Tang, Huaimei Zhang, Lijuan Wang, Lichong Yang, Shuangxu Tan, Zhimei Yuan, Ce Han, Lili He, Yuping Zheng, Fenglan Zhao, Lijie Guo, Ligang Jiang, Jinfeng Li, Yongfei Jiang, Xuexia Zou, Dan Xu, Han Xu, Xiaojia Wang, Yingbin Qi, Xuefeng Hu, Yu Zhang, Zhen‐Ni Guo, Hang Jin, on behalf of the Biomarkers of Brain Injury Investigator Study Group   +28 more
wiley   +1 more source

The Case of a 28‐Year‐Old Woman With Medically Refractory Focal Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We present the case of a 28‐year‐old right‐handed woman with medically refractory focal epilepsy. Her seizure semiology and electroencephalography (EEG) indicated a seizure onset zone in the right central‐parietal area. However, both MRI and PET scans were unremarkable, showing no focal lesions or areas of altered metabolism.
Rishi Sharma, Ilo Leppik, Thomas Henry, Thaddeus Walczak, Sima Patel, Robert McGovern   +5 more
wiley   +1 more source

S-Nitrosoglutathione induces ciliary neurotrophic factor expression in astrocytes, which has implications to protect the central nervous system under pathological conditions. [PDF]

, 2013
Manjeet K. Paintlia, Ajaib S. Paintlia, Avtar Singh, Inderjit Singh   +3 more
openalex   +1 more source

CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2011-2015.

Neuro-Oncology, 2018
Q. Ostrom, H. Gittleman, Gabrielle Truitt, Alexander L. Boscia, C. Kruchko, J. Barnholtz-Sloan   +5 more
semanticscholar   +1 more source

Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19

Nature Neuroscience, 2020
J. Meinhardt, Josefine Radke, Carsten Dittmayer, J. Franz, C. Thomas, R. Mothes, M. Laue, J. Schneider, Sebastian Brünink, Selina Greuel, Malte Lehmann, Olga Hassan, T. Aschman, E. Schumann, R. Chua, C. Conrad, R. Eils, W. Stenzel, M. Windgassen, L. Rößler, H. Goebel, H. Gelderblom, H. Martin, A. Nitsche, W. Schulz-Schaeffer, S. Hakroush, M. Winkler, Björn Tampe, F. Scheibe, Péter Körtvélyessy, D. Reinhold, B. Siegmund, A. Kühl, S. Elezkurtaj, D. Horst, L. Oesterhelweg, M. Tsokos, B. Ingold‐Heppner, C. Stadelmann, C. Drosten, V. Corman, H. Radbruch, F. Heppner   +42 more
semanticscholar   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source

Deep Learning–Assisted Differentiation of Four Peripheral Neuropathies Using Corneal Confocal Microscopy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah, Ioannis N. Petropoulos, Mark Stettner, Maryam Ferdousi, Uazman Alam, Nathan Efron, Ahmed Serag, Rayaz A. Malik   +7 more
wiley   +1 more source