Results 71 to 80 of about 1,581,852 (393)

Automated Analysis of Cryptococcal Macrophage Parasitism Using GFP-Tagged Cryptococci [PDF]

, 2010
The human fungal pathogens Cryptococcus neoformans and C. gattii cause life-threatening infections of the central nervous system. One of the major characteristics of cryptococcal disease is the ability of the pathogen to parasitise upon phagocytic immune
A Casadevall, A Idnurm, AL Goldstein, B Bolanos, BJ Park, C Charlier, C Luberto, C Monari, CE Cross, DA Bobak, DL Goldman, DL Goldman, DL Oliveira, DL Toffaletti, E Brummer, EJ Byrnes 3rd, F Chretien, FM Griffin Jr, G Hu, GD Campbell, GS Bulmer, GS Bulmer, H Lee, H Ma, H Ma, H Ma, HF Nadrous, J Livet, Julian C. Rutherford, K Voelz, Kerstin Voelz, Kirsten Nielsen, L MacDougall, LA Knodler, LH Okagaki, M Alvarez, M Alvarez, M Alvarez, M Alvarez, M Del Poeta, M Feldmesser, M Feldmesser, M Shi, MC Lorenz, MF Miller, NC Shaner, P Ralph, R Bajpai, R Santangelo, R Velagapudi, RD Diamond, Robin C. May, S Geunes-Boyer, SC Tucker, SE Kidd, Simon A. Johnston, SM Levitz, TA Missall, TB Kechichian, TG Mitchell, TG Mitchell, TR Kozel, TW Christianson, X Dong, X Shao   +64 more
core   +5 more sources

Microglia in diseases of the central nervous system

Annals of Medicine, 2002
Microglia (MG) are enigmatic cells of the central nervous system (CNS). MG are morphologically, antigenically and functionally flexible, and have the potential for mobility and proliferation. MG are professional antigen-presenting cells and constitute part of the local CNS innate immune system, communicating with other immune cells via chemokines ...
Ehud Lavi, Peter T. Nelson, Lorinda Soma
openaire   +3 more sources

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Demyelinating Disease? Central Nervous System Lymphoma?

Türk Nöroloji Dergisi, 2008
Scientific backgound: Primary lymphomas of the central nervous system (CNS) consist of about 1% of brain tumors. Primary central nervous system lymphoma (PSSSL) is a non-Hodgkin’s lymphoma restricted to the nervous system.
Ufuk Ergün, Abidin Erdal, Bahar Say, Ruhat Karahan, Levent İnan, Figen Söylemezoğlu, Hakan Oruçkaptan   +6 more
doaj  

Metastatic Cardiac Angiosarcoma to the Lung, Spine, and Brain: A Case Report and Review of the Literature [PDF]

, 2017
Background Metastatic angiosarcoma to the brain is a rare entity without an established management protocol. Case Description A man with primary cardiac angiosarcoma presented with a rare brain metastasis.
Ducis, Katrina, Lin, Chih-Ta, Tranmer, Bruce, Tucker, Suzanne   +3 more
core   +1 more source

Searching for clues: tracking the pathogenesis of human immunodeficiency virus central nervous system disease by use of an accelerated, consistent simian immunodeficiency virus macaque model.

Journal of Infectious Diseases, 2002
An accelerated model of human immunodeficiency virus central nervous system disease was developed in which more than 90% of infected macaques develop typical simian immunodeficiency virus (SIV) encephalitis with neuronal dysfunction by postinoculation ...
J. Mankowski, J E Clements, M. Zink
semanticscholar   +1 more source

Role of Exosomes in Central Nervous System Diseases [PDF]

Frontiers in Molecular Neuroscience, 2019
There are many types of intercellular communication, and extracellular vesicles are one of the important forms of this. They are released by a variety of cell types, are heterogeneous, and can roughly be divided into microvesicles and exosomes according to their occurrence and function.
Wanying Liu, Wanying Liu, Wanying Liu, Xiaodan Bai, Xiaodan Bai, Xiaodan Bai, Ao Zhang, Juanjuan Huang, Juanjuan Huang, Juanjuan Huang, Shixin Xu, Shixin Xu, Junping Zhang   +12 more
openaire   +4 more sources

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

Molecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul, François Guillonneau, Odile Blanchet, Hamza Lasla, Audrey Rousseau, Catherine Guette, Alice Boissard, Cécile Henry, Morgan Dhondt, Pascal Jézéquel, Philippe Menei, Jean‐Michel Lemée   +11 more
wiley   +1 more source

Central nervous system Listeria monocytogenes infection mimicking central nervous system idiopathic inflammatory demyelinating disease

Infection and Drug Resistance, 2019
Rui Xu,1,* Yang Bai,2,* Chunmei Duan,1 Shifu Zhao,1 Xiaoyan Chen,1 Qingwu Yang1 1Department of Neurology, Xinqiao Hospital and The Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing 400037, China ...
Xu R, Bai Y, Duan C, Zhao S, Chen X, Yang Q   +5 more
doaj  

Design and construction of a distributed sensor NET for biotelemetric monitoring of brain energetic metabolism using microsensors and biosensors [PDF]

, 2010
Neurochemical pathways involved in brain physiology or disease pathogenesis are mostly unknown either in physiological conditions or in neurodegenerative diseases.
Bazzu, Gianfranco, Calia, Giammario, Migheli, Rossana, Puggioni, Giulia, Rocchitta, Gaia Giovanna Maria, Serra, Pier Andrea   +5 more
core   +2 more sources