Results 191 to 200 of about 429,016 (241)

Machine Learning Enhanced Multimodal Bioelectronics: Advancement Toward Intelligent Healthcare Systems

Advanced Sensor Research, EarlyView.
This review examines recent advancements in multimodal bioelectronics, emphasizing machine learning integration to enhance functionality. The application of machine learning methodologies improving biosignal processing, device adaptability, and diagnostic accuracy is discussed to introduce Machine Learning enhanced bioelectronics as a pathway toward ...
Myoungjae Oh, Enji Kim, Jakyoung Lee, Inhea Jeong, Eunmin Kim, Joonho Paek, Taekyeong Lee, Dayeon Kim, Seung Hyun An, Sumin Kim, Jung Ah Lim, Jang‐Ung Park   +11 more
wiley   +1 more source

Natural flavonoids from herbs and nutraceuticals as ferroptosis inhibitors in central nervous system diseases: current preclinical evidence and future perspectives. [PDF]

Front Pharmacol
Li Q, Yang X, Li T.
europepmc   +1 more source

Microneedles for Continuous, Minimally Invasive Monitoring: A Technology Overview

Advanced Sensor Research, EarlyView.
This review explores recent advances in electrochemical sensing using microneedles—small, minimally invasive devices that access interstitial fluid for real‐time molecular monitoring. It highlights fabrication methods, materials, and biosensor development, with a focus on aptamer‐based sensing. The review also discusses current applications, challenges,
Guillermo Conejo‐Cuevas, Miguel Aller Pellitero, Leire Ruiz‐Rubio, Francisco Javier del Campo   +3 more
wiley   +1 more source

A Wonderful Journey: The Diverse Roles of Adenosine Deaminase Action on RNA 1 (ADAR1) in Central Nervous System Diseases. [PDF]

CNS Neurosci Ther
Cheng L, Liu Z, Shen C, Xiong Y, Shin SY, Hwang Y, Yang SB, Chen Z, Zhang X.   +8 more
europepmc   +1 more source

Emerging Therapeutic Strategies for Hearing Loss

Advanced Therapeutics, EarlyView.
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han, Tian Shen, Weiwei He, Hao Wei, Xiaolong Zhao, Wen Yang, Chuan Bu, Xinghua Tang, Yu Zhao, Jiangang Fan   +9 more
wiley   +1 more source

Immune Checkpoint PD‐L1 Modulates Retinal Microglial Activation to Alleviate Vascular Leakage in Choroidal Neovascularization via ERK

Advanced Science, EarlyView.
PD‐L1 limits neuroinflammation in neovascular AMD by modulating microglial activation. Its deficiency exacerbates vascular leakage and choroidal neovascularization (CNV) via ERK signaling, while enhancing PD‐L1 reduces inflammation and neovascularization. Targeting PD‐L1 may offer a novel immunomodulatory strategy for NVAMD.
Yue Zou, Junliang Jiang, Yunqin Li, Xinyi Ding, Qiuping Tong, Ying Shi, Lei Xiao, Ling Chen   +7 more
wiley   +1 more source

AB0081 Central nervous system involvement in connective tissue diseases – our expirience

, 2001
DZ Stefanovic, BC Glisic, MM Cirkovic, ZV Andjlekovic, MR Petronijevic, D Mitrović, M Popović   +6 more
openalex   +1 more source

Accelerated Bone Healing via Electrical Stimulation

Advanced Science, EarlyView.
Electrical stimulation significantly impacts bone healing by enhancing osteoblast proliferation, differentiation, and vascularization through calmodulin/calcineurin/NFAT signaling. It also boosts macrophage function and cell migration, presenting a comprehensive approach to accelerating bone repair.
Jianfeng Sun, Wenqing Xie, Yuxiang Wu, Zhou Li, Yusheng Li   +4 more
wiley   +1 more source

Inhibition of Rho GTPases with Protein Prenyltransferase Inhibitors Prevents Leukocyte Recruitment to the Central Nervous System and Attenuates Clinical Signs of Disease in an Animal Model of Multiple Sclerosis

, 2002
Claire E. Walters, Gareth Pryce, Deborah J.R. Hankey, Saı̈d M. Sebti, Andrew D. Hamilton, David Baker, John Greenwood, Peter Adamson   +7 more
openalex   +1 more source

FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron

Advanced Science, EarlyView.
This study aimed to unravel the role of FUS in the loading of functional circRNAs into neuronal sEVs under hypoxic conditions, which involves their aggregations in SGs and specific interaction between the FUS Zf_RanBP domain to regulate circRNA sorting in sEVs.
Jiankun Zang, Yousheng Wu, Xuanlin Su, Kaiwei Cai, Man Ke, Niu He, Huili Zhu, Zefeng Tan, Jielin Zhu, Wensheng He, Min Peng, Shiqing Zhang, Hongcheng Mai, Anding Xu, Dan Lu   +14 more
wiley   +1 more source