Results 101 to 110 of about 185,500 (340)

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Exploiting the Impact of Sociodemographics in the Diagnosis of Central Nervous System Tumors in Childhood

Brazilian Journal of Oncology
Introduction Central nervous system (CNS) tumors are the most common solid tumors in childhood, comprising 20% of all neoplasms in that age.
Marcela Yasmin Leroy, Luiz Fernando Lopes, Raniela Ferreira Faria, Thaissa Maria Veiga Faria, Denise Leonardi Queiroz Prado, Welinton Yoshio Hirai, Bruna Minniti Mançano   +6 more
doaj   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Dural metastases from prostatic cancer or chronic subdural hematoma

Revista Ciencias Biomédicas, 2012
Introduction: dural metastases of prostatic adenocarcinoma appear in advanced stagesof the disease and they can be the first manifestation of a prostatic carcinoma, evenwithout urological symptoms.Clinical case: a 71 year-old patient without previous ...
Taboada-Lora Luis Roberto, Bernal-Bernal David Alejandro, Navarro-Tovar Saúl   +2 more
doaj  

Cervicomedullary intramedullary peripheral primitive neuroectodermal tumor with intratumoral bleed: Report of one case and review of literature

Journal of Craniovertebral Junction and Spine, 2016
Primitive neuroectodermal tumors (PNET) are highly malignant, yet relatively uncommon neoplasms of the central nervous system. Although a host of different parts of the nervous system can be affected, intramedullary location of PNET is extremely rare ...
Pradeep Sharma, Kuntal K Das, Anant Mehrotra, Arun K Srivastava, Rabi N Sahu, Awadhesh Jaiswal, Rakesh Pandey, Sanjay Behari, Kamlesh S Bhaisora, Jayesh Sardhara   +9 more
doaj   +1 more source

Metastatic Malignant Neoplasm in the Central Nervous System [PDF]

, 2020
National Cancer Institute
openalex   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Risk of Second Primary Neoplasms of the Central Nervous System

, 2022
Elisa K. Liu, Cheongeun Oh, Douglas Kondziolka, Erik P. Sulman   +3 more
openalex   +1 more source

Utility of Preoperative Blood-Oxygen-Level–Dependent Functional MR Imaging in Patients with a Central Nervous System Neoplasm [PDF]

, 2020
Ammar Chaudhry, Sohaib Naim, Maryam Gul, Abbas Chaudhry, Mike Y. Chen, Rahul Jandial, Behnam Badie   +6 more
openalex   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source