Results 111 to 120 of about 185,500 (340)
NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao +10 more
wiley +1 more source
Mortality Trends of Brain and Central Nervous System Cancers in Babol, Northern Iran (2013-2021) [PDF]
Caspian Journal of Internal MedicineBackground: Cancers of the brain and central nervous system, with more than 250,000 deaths in 2020 and an age-adjusted mortality rate of 3.05 per 100,000, rank twelfth in mortality among various cancers.
Mohsen Karami +5 more
doaj
Imaging evaluation of central nervous system tumor heterogeneity
Chinese Journal of Contemporary Neurology and Neurosurgery, 2018 Different tumors and different levels of the same tumor in central nervous system (CNS) show tumor heterogeneity accordingly. Tumor heterogeneity is not only reflected in antigen, histopathology and immunology, but also reflected in different types of ...
Kai XU, Yue DAI
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini +13 more
wiley +1 more source
Image and Histologic Characterization of Intracranial Neoplasias
Medisur, 2011 Background: In Cuba, as in all developed countries, cancer is the second cause of death and among it the different types of intracranial neoplasms present a morbidity of 2-3 %.
Martha Yudey Rodríguez Pino +5 more
doaj +2 more sources
The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen +5 more
wiley +1 more source
Molecular pathology and targeted therapy of common tumors in central nervous system
Chinese Journal of Contemporary Neurology and Neurosurgery, 2014 It is difficult to cure central nervous system tumors using traditional method, due to chemotherapy drugs lack of specificity. They kill the tumor cells, and damage normal tissues and organs at the same time.
Fei YANG, Yue-shan PIAO, De-hong LU
doaj
The role of frailty in geriatric cranial neurosurgery for primary central nervous system neoplasms [PDF]
, 2020 Shane Shahrestani +10 more
openalex +1 more source
Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan +22 more
wiley +1 more source