Results 51 to 60 of about 5,479 (148)

A Polytropic Caprine Arthritis Encephalitis Virus Promoter Isolated from Multiple Tissues from a Sheep with Multisystemic Lentivirus-Associated Inflammatory Disease [PDF]

, 2013
Caprine arthritis encephalitis virus (CAEV) is a lentivirus that infects both goats and sheep and is closely related to maedi-visna virus that infects sheep; collectively, these viruses are known as small ruminant lentiviruses (SRLV).
Adeyemi O. Adedeji, Bradd Barr, Brian Murphy, Esperanza Gomez-Lucia   +3 more
core   +4 more sources

Challenges and Opportunities in State‐of‐the‐Art Proteomics Analysis for Biomarker Development From Plasma Extracellular Vesicles

PROTEOMICS, Volume 26, Issue 2-3, Page 9-20, February 2026.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound particles secreted by cells, playing crucial roles in intercellular communication. The composition of EVs can undergo changes in response to stress and disease conditions, making them excellent biomarker candidates.
Panshak P. Dakup, Ivo Diaz Ludovico, Youngki You, Chaitra Rao, Javier Flores, Lisa M. Bramer, Marian Rewers, Bobbie‐Jo M. Webb‐Robertson, Thomas O. Metz, Raghavendra G. Mirmira, Emily K. Sims, Ernesto S. Nakayasu   +11 more
wiley   +1 more source

Cortisol Regulates PD‐1 and IL‐12 in Canine Leishmaniasis

Parasite Immunology, Volume 48, Issue 2, February 2026.
ABSTRACT Canine visceral leishmaniasis (CanL) is a tropical zoonosis caused by Brazil's protozoan Leishmania (L.) infantum. Disorders in the hypothalamic–pituitary–adrenal (HPA) axis have been reported in human and experimental visceral leishmaniasis, but not yet in canine leishmaniasis.
Lucas Takeshi Siqueira Ito, Gisele Mitsue Umino, Mayla Abbas Guimarães, Bianca Maciel Marques de Souza, Sofia Furrier Soares, Luiz Eduardo Amador Loiola Pereira, Valéria Marçal Felix de Lima   +6 more
wiley   +1 more source

Pharmacology of DB844, an orally active aza analogue of pafuramidine, in a monkey model of second stage human African trypanosomiasis [PDF]

, 2012
Novel drugs to treat human African trypanosomiasis (HAT) are still urgently needed despite the recent addition of nifurtimox-eflornithine combination therapy (NECT) to WHO Model Lists of Essential Medicines against second stage HAT, where parasites have ...
Boykin, D. W., Brun, R., Ching, S., Denton, C. L., Hall, J. E., Kagira, J. M., Mdachi, R. E., Murilla, G. A., Paine, M. F., Thuita, J. K., Tidwell, R. R., Wang, M. Z.   +11 more
core   +5 more sources

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, Volume 36, Issue 1, 2 January 2026.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

9‐Deoxymuzigadial, a Sesquiterpene Isolated From Drimys brasiliensis (Winteraceae), Displays Reduced Cytotoxicity In Vitro and Modulates Leukocyte Activity and Fibrogenesis In Vivo

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT The aims of this study were to investigate in vitro cytotoxic potential and the effects of daily administration during the inflammatory response induced by sponge implants in mice of the sesquiterpene 9‐deoxymuzigadial (9‐DOM), isolated from Drimys brasiliensis (Winteraceae).
Bruno Antonio Ferreira, Isabella Silva Cassimiro, Francyelle Borges Rosa de Moura, Tais de Campos Lima, Danielle Reis Napolitano, Eric Umehara, João Henrique Ghilardi Lago, Fernanda de Assis Araújo   +7 more
wiley   +1 more source

1,4-disubstituted thiosemicarbazide derivatives are potent inhibitors of toxoplasma gondii proliferation. [PDF]

, 2014
A series of 4-arylthiosemicarbazides substituted at the N1 position with a 5-membered heteroaryl ring was synthesized and evaluated in vitro for T. gondii inhibition proliferation and host cell cytotoxicity.
Dzitko, Katarzyna, Paneth, Agata, Paneth, Piotr, Pawełczyk, Jakub, Plech, Tomasz, Stefańska, Joanna, Stączek, Paweł   +6 more
core   +2 more sources

Culture-independent genome sequencing of clinical samples reveals an unexpected heterogeneity of infections by chlamydia pecorum [PDF]

, 2015
Copyright © 2015, American Society for Microbiology. All Rights Reserved. Chlamydia pecorum is an important global pathogen of livestock, and it is also a significant threat to the long-term survival of Australia's koala populations.
Bachmann, NL, Jelocnik, M, Myers, GSA, Polkinghorne, A, Sullivan, MJ, Timms, P   +5 more
core   +1 more source

Traditional Medicine Practices among Community Members with Diabetes Mellitus in Northern Tanzania: An ethnomedical Survey. [PDF]

, 2016
Diabetes is a growing burden in sub-Saharan Africa where traditional medicines (TMs) remain a primary form of healthcare in many settings. In Tanzania, TMs are frequently used to treat non-communicable diseases, yet little is known about TM practices for
Daphne Wang, David Boyd, Francis Karia, John W. Stanifer, Joseph Lunyera, Justin Omolo, null null, Uptal D. Patel, Venance Maro   +8 more
core   +3 more sources

The susceptibility of pathogenic free-living amebae to chemotherapeutic agents : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Microbiology at Massey University [PDF]

, 1979
The treatment of infections caused by pathogenic free-living amebae (PFLA) has, until only recently, been far from successful. The continued screening of chemotherapeutic agents against amebae of the genera Naegleria and Acanthamoeba is therefore of the ...
Donald, Jennifer Jane
core