Results 231 to 240 of about 22,295,129 (298)

Real-World Evidence on Short-Term Weight Changes Following Methylphenidate Use in Pediatric Population: A Retrospective Study Using Common Data Model. [PDF]

Clin Transl Sci
Lee H, Park EG, Yang HJ, Seo YG, Kang DY, Kim C, Sim DW, Seo J, Kim SH, Cho D, Kim K, Lee J, Kim Y, Lee K, Park HK, Joo HJ, Choi IY, An TJ, Moon MH, Jeong C, Im S, Ko SW, Lee JY, Chung YW, Kim YY, Shin SJ, Kim B, Sohn SJ.   +27 more
europepmc   +1 more source

Optical Windows for Transcranial Brain Imaging in Living Mice: Skull Thinning, Clearing, and Beyond

Advanced Science, EarlyView.
Longitudinal, noninvasive in vivo imaging is crucial for studying brain physiology. Advances in transcranial optical windows and multiphoton microscopy have improved imaging depth, but their performance often deteriorates over time. This work investigated various transcranial window approaches and found that skull regrowth limits image quality.
Yiming Fu, Gewei Yan, Zhentao She, Yingzhu He, Kangqi Liu, Jianan Qu   +5 more
wiley   +1 more source

Validation of the Stimulant Use Motives Scale and Assessment of Its Associations with Psychosocial Functioning and Sexual Health in U.S. Men Who Have Sex with Men. [PDF]

Subst Use Misuse
Esquivel-Mendoza JA, Weinstein ER, Porras A, Pantalone DW, Biello KB, Mayer K, Mimiaga MJ, Safren SA.   +7 more
europepmc   +1 more source

RBM12 Maintains Glioma Stem Cells by Activating Amino Acid‐Dependent mTORC1 Signaling via SLC7A5 mRNA Stabilization

Advanced Science, EarlyView.
This study shows that in glioma stem cells (GSCs), RBM12 recruits ALKBH5 to remove m6A from SLC7A5 transcripts, thereby enhancing mRNA stability, which elevates large neutral amino acid (LNAA) levels and activates mTORC1, promoting GSC proliferation, self‐renewal, and tumor growth.
Hong Lei, Wenlong Luo, Shu Zhou, Lihao Wan, Peng Ling, Zhihua Huang, Zhihua Qian, Chenfei Lu, Mengyue Guo, Zhen Xue, Jun Qin, Ningwei Zhao, Jianghong Man, Wenchao Zhou, Zhiqiang Dong, Shutong Xu, Zhipeng Zhou, Xiuxing Wang, Weiwei Tao   +18 more
wiley   +1 more source

Targeting the Carotid Body Function With Big-K⁺-Channel Blocker ENA-001 in Opioid-Induced Respiratory Depression: A Scoping Review. [PDF]

Pharmacol Res Perspect
Arevalo JJ, van Velzen M, Jansen SC, van Lemmen M, Sarton E, Dahan A, Olofsen E, Cotten JF, Niesters M, van der Schrier RM.   +9 more
europepmc   +1 more source

Multi‐Component Functionalized Bifidobacterium Longum Hydrogel for Multi‐Target Integrated Therapy of Colitis‐Associated Anxiety and Depression

Advanced Science, EarlyView.
A pH/MMP dual‐responsive Bifidobacterium longum (BL) hydrogel (INPs@BL@Gel) functionalized with baicalin, tyrosine, and inulin is constructed. It enables gastric protection, inflammation‐targeted release, and prolonged intestinal colonization. By remodeling gut microbiota, elevating beneficial neuroactive metabolites (homovanillic acid, short‐chain ...
Shuo Zhang, Yujie Zhang, Jiansheng He, Shunlian Li, Qingyan Ma, Qiao Li, Yudan Zhang, Yiyang Wang, Shaobo Ma, Songyan Jin, Chune Li, Xueyong Xie, Hang Zhang, Junze Deng, Xueqin Song, Daocheng Wu, Xiancang Ma, Feng Zhu   +17 more
wiley   +1 more source

Neurochemical and Genetic Alterations in Chronic Stimulant (Crystal and Captagon) Users: A Comparative Analysis of Monoamine Biomarkers and Addiction-Related Gene Expression. [PDF]

Biochem Res Int
Jasim YH, Al-Mashhdani BA, Abd-Almajeed Abd-Alkareem M, Shah Bukhari AA, Jasim RH, Tabasum S, Hasanli L, Khan R.   +7 more
europepmc   +1 more source

Late adolescent nonmedical prescription stimulant sources and links to young adult nonmedical stimulant use and sources. [PDF]

Addict Behav
Schepis TS, McCabe SE, West BT, Ford JA, Jardine J, Veliz PT.   +5 more
europepmc   +1 more source

A Review of Kratom Product Evolution and Its Associated Health Outcomes. [PDF]

Subst Abuse Rehabil
Aly S, Grundmann O.
europepmc   +1 more source

Patterns of prescription stimulant initiation before and during the COVID-19 pandemic: a population-based time-series analysis. [PDF]

CMAJ
Gomes T, Wang T, Rebić N, Miller S, Paolozza L, Vigod SN, Tadrous M.   +6 more
europepmc   +1 more source