Results 41 to 50 of about 2,340 (196)

CCDC26, CDKN2BAS, RTEL1 and TERT Polymorphisms in pediatric brain tumor susceptibility [PDF]

, 2017
The role of genetic polymorphisms in pediatric brain tumor (PBT) etiology is poorly understood. In this study, we tested the hypothesis that single nucleotide polymorphisms identified by genome-wide association studies on adult glioma are also associated
Adel Fahmideh, Maral, Feychting, Maria, Grotzer, Michael A., Johansen, Christoffer, Kuehni, Claudia E., Lannering, Birgitta, Lavebratt, Catharina, Prochazka, Michaela, Röösli, Martin, Schmidt, Lisbeth S., Schüz, Joachim, Tynes, Tore   +11 more
core   +1 more source

Atypical central neurocytoma with leptomeningeal dissemination: a case report

Journal of the Egyptian National Cancer Institute, 2020
Background Central neurocytomas represent 0.25–0.5% of all intracranial tumors in adults. Leptomeningeal spread is uncommon, and the exact incidence of meningeal spread is unknown due to sparse literature.
Shikha Goyal, Tejinder Kataria, Deepak Gupta, Aruj Dhyani, Ishani Mohapatra, Karanjit Singh Narang   +5 more
doaj   +1 more source

Exploring the interdependencies of research funders in the UK [PDF]

, 2014
Investment in medical research is vital to the continuing improvement of the UK's health and wealth. It is through research that we expand our understanding of disease and develop new treatments for patients.
Crane, P, Farrell, C, Garau, M, Grassano, N, Hernandez-Villafuerte, K, Hopkins, M M, Hutton, J, Lang, F, Mawer, A, Pateman, C, Rotolo, D, Shah, K, Sharp, T, Sussex, J   +13 more
core   +1 more source

Single‐Cell Dissection of the Biological Function and Molecular Features Underlying the Micropeptide LSMEM1 in Kidney

Advanced Science, Volume 12, Issue 48, December 29, 2025.
LSMEM1, an evolutionarily conserved micropeptide with extreme hydrophobicity (aliphatic index═113) and dynamic amphiphilicity (GRAVY═0.017), features a strong α‐helical transmembrane anchor (residues 64‐86). Single‐cell analysis reveals its critical role in renal lipid homeostasis.
Peimin Liu, Hong Zhang, Shanzhi Yang, Jiaoqing Li, Danfeng Wu, Haosen Xu, Huan Jiang, Yi Jing, Guoxiang Jin, Ruobing Liu, Ning Fan, Xiaoyan Bai   +11 more
wiley   +1 more source

Diffuse GFAP Immunopositivity in the Oligodendrocyte-like Component of Pilocytic Astrocytoma Distinguishes It from Mimickers

Diagnostics, 2022
Pilocytic astrocytoma with a predominant oligodendrocyte-like component can be difficult to distinguish from oligodendroglioma, dysembryoplastic neuroepithelial tumors (DNTs), central neurocytoma, and ependymoma (clear cell phenotype).
Murad Alturkustani
doaj   +1 more source

Rosette-forming glioneuronal tumor: a pineal region case with IDH1 and IDH2 mutation analyses and literature review of 43 cases [PDF]

, 2010
Rosette-forming glioneuronal tumor (RGNT) of the fourth ventricle is a mixed glio-neuronal neoplasm recently codified by the World Health Organization WHO Classification of Central Nervous System (CNS) Tumors (2007). To date, 43 cases have been described
Orestes E. Solis, Rupal I. Mehta, Albert Lai, Rashi I. Mehta, Lama O. Farchoukh, Richard M. Green, Jerry C. Cheng, Sathima Natarajan, Harry V. Vinters, Timothy Cloughesy, William H. Yong   +10 more
core   +2 more sources

A Rare Case of Extra-Ventricular Supra-Sellar Neurocytoma – A Diagnostic Conundrum [PDF]

, 2022
The brain and its associated structures are often the primary source or site of metastases for many tumors. Neurocytoma is a relatively rare neuronal neoplasm, first described as an intra-ventricular tumor that is not known to be very aggressive.
Karkra, Rohan, Keerthi, Peri, Satish, Suchitha   +2 more
core   +2 more sources

Molecular Landscape of Pediatric Low‐Grade Gliomas: Insights From RNA‐NGS and Bioinformatic Analysis

Genes, Chromosomes and Cancer, Volume 64, Issue 10, October 2025.
ABSTRACT Pediatric low‐grade gliomas (pLGG) are the most common group of childhood brain tumors. Genetic alterations in the RAS–RAF–mitogen‐activated protein kinase (MAPK) pathway are the molecular drivers in the vast majority of pLGG. A large proportion of pediatric pLGG are characterized by the presence of fusion genes.
Petr Brož, Martina Strnadová, Denisa Olejníková, Johana Kotiš, Tereza Pospíšilíková, Adéla Mišove, Miroslav Koblížek, Josef Zámečník, Michal Zápotocký, David Sumerauer, Aleš Vícha, Martin Kynčl, Petr Libý, Vladimír Beneš, Lenka Krsková   +14 more
wiley   +1 more source

Intraoperative cytology of central neurocytoma mimicking oligodendroglioma

Journal of Cytology, 2011
Central neurocytomas (CNs) are uncommon tumors of the central nervous system. These tumors have a predilection for the lateral ventricles of young adults and are known to display characteristic neuroimaging and histomorphologic features.
Prabal Deb, Prateek Kinra, Harjinder Singh Bhatoe   +2 more
doaj   +1 more source

Tumor‐related epilepsy in glioma: A multidisciplinary overview

Epilepsia, Volume 66, Issue 10, Page 3621-3641, October 2025.
Abstract Seizures are a common and challenging symptom in brain tumors, affecting approximately 60% of patients. Tumor‐related epilepsy (TRE) in glioma patients requires personalized and dynamic management in a multidisciplinary environment, especially for its intricate pathophysiology and unpredictable disease evolution. This investigation provides an
Roberto Michelucci, Giada Pauletto, Antonio Silvani, Elena Pasini, Tamara Ius, Matteo Martinoni, Carlo Alberto Castioni, Andrea Salmaggi, Sofia Asioli, Marta Maschio, Giuseppe Minniti, Enrico Franceschi, Flavio Villani, Roberta Rudà, Eleonora Aronica, the Italian Multidisciplinary Group for Tumor Epilepsy, Paolo Vitali, Damiano Balestrini, Elisa D’Angelo, Lorenzo Bello, Marco Rossi, Marta Padovan, Anna Teresa Giallonardo, Carlo di Bonaventura, Francesco Toni, Angela La Neve, Simona Rizzato, Matteo Pugnaghi, Marco Vindigni, Carmelo Sturiale   +29 more
wiley   +1 more source