Results 21 to 30 of about 21,714 (253)

The critical BMI hypothesis for puberty initiation and the gender prevalence difference: Evidence from an epidemiological survey in Beijing, China

Frontiers in Endocrinology, 2022
BackgroundAlthough previous studies suggested that there is a certain level of body fat mass before puberty can be initiated, most studies have focused on girls.ObjectiveTo investigate the relationship between precocious puberty and physical growth in ...
Meijuan Liu, Bingyan Cao, Qipeng Luo, Qiao Wang, Min Liu, Xuejun Liang, Di Wu, Wenjing Li, Chang Su, Jiajia Chen, Chunxiu Gong   +10 more
doaj   +1 more source

Central Precocious Puberty Following Treatment of Precocious Pseudo-Puberty Caused by Leydig Cell Tumor: A Pediatric Case and Literature Review

Clinical Pediatric Hematology-Oncology, 2022
Leydig cell tumors can cause precocious puberty in prepubertal males. Radical orchiectomy is the standard therapy for Leydig cell tumors, with a good overall prognosis.
Jeong Ho Ahn, Ji Kyoung Park, Soo Jin Jung, Jeong Eun Lee   +3 more
doaj   +1 more source

Gut microbiome combined with metabolomics reveals biomarkers and pathways in central precocious puberty

Journal of Translational Medicine, 2023
Background Central precocious puberty (CPP) is a common disease in prepubertal children and results mainly from disorders in the endocrine system. Emerging evidence has highlighted the involvement of gut microbes in hormone secretion, but their roles and
Xiaoyan Huang, Jixiong Chen, Haozhe Zou, Peng Huang, Hailing Luo, Haidan Li, Yuhua Cai, Li Liu, Yongsheng Li, Xiaojie He, Wei Xiang   +10 more
semanticscholar   +1 more source

Is precocious puberty linked to hypothalamic expression of arginine-phenylalanine-amide-related peptide? [PDF]

Iranian Journal of Basic Medical Sciences, 2017
The up-regulator regulation and down-regulator regulation of gonadotropin-releasing hormone (GnRH) in central precocious puberty is not yet known. However, recent advances in neuroendocrinology have shown the controlling role of arginine-phenylalanine ...
Yuanyuan He, Wen Sun, Jian Yu
doaj   +1 more source

Causes of Precocious Puberty in Children Referred to an Endocrine Clinic in Qazvin City, Iran From 2006 to 2018

Journal of Pediatrics Review, 2021
Background: Puberty is an essential milestone in a person’s life. Studies show that precocious puberty is more common in girls than in boys. Objectives: The aim of this study was to survey the causes of precocious puberty in children referred to the ...
Fatemeh Saffari, Roghayeh Golmohammadi, Ali Homaei   +2 more
doaj   +1 more source

Rare Variants in the MECP2 Gene in Girls with Central Precocious Puberty

The Lancet Diabetes and Endocrinology, 2023
Background Identification of genetic causes of central precocious puberty (CPP) has revealed epigenetic mechanisms as regulators of human pubertal timing. Methyl-CpG-binding protein 2 (MECP2), an X-linked gene, encodes a chromatin-associated protein with
A. Canton, F. Tinano, L. Guasti, L. Montenegro, F. Ryan, Deborah Shears, M. E. de Melo, L. Gomes, Mariana P. Piana, R. Brauner, R. E. Aguilar, Arancha Escribano-Muñoz, Alyssa J J Paganoni, Jordan E Read, M. Korbonits, C. Seraphim, S. Costa, A. Krepischi, A. Jorge, A. David, L. R. Kaisinger, Ken K. Ong, J. Perry, A. Abreu, U. Kaiser, J. Argente, B. Mendonca, V. Brito, S. Howard, A. Latronico   +29 more
semanticscholar   +1 more source

Familial central precocious puberty due to DLK1 deficiency: novel genetic findings and relevance of serum DLK1 levels.

European Journal of Endocrinology, 2023
BACKGROUND Several rare loss-of-function mutations of delta-like noncanonical notch ligand 1 (DLK1) have been described in non-syndromic children with familial central precocious puberty (CPP).
L. Montenegro, C. Seraphim, F. Tinano, M. Piovesan, A. Canton, K. McElreavey, S. Brabant, Natalia P Boris, M. Magnuson, R. Carroll, U. Kaiser, J. Argente, V. Barrios, V. Brito, R. Brauner, A. Latronico   +15 more
semanticscholar   +1 more source

Effects of the COVID-19 pandemic on the incidence of central precocious puberty; a narrative review

Journal of Pediatric Endocrinology & Metabolism (JPEM), 2023
Central precocious puberty (CPP) is the premature activation of the hypothalamus–pituitary–gonadal axis, resulting in the early development of secondary sexual characteristics. CPP classically occurs before the age of 8 years in girls and 9 years in boys.
Rebecca B. Hoskyns, Sasha R. Howard
semanticscholar   +1 more source

Analysis of serum insulin-like growth factor-1, fibroblast growth factor 23, and Klotho levels in girls with rapidly progressive central precocious puberty

European Journal of Pediatrics, 2023
To study the levels of serum insulin-like growth factor 1 (IGF-1), fibroblast growth factor 23 (FGF23), and Klotho, and to study their relationship with girls with rapidly progressive central precocious puberty (RP-CPP).
Yuping Liu, Yaying Cheng, Meng Sun, Xiaojing Hao, Mengmeng Li   +4 more
semanticscholar   +1 more source

COVID-19 lockdown and the rate of central precocious puberty

Journal of Endocrinological Investigation, 2023
The aim of our study was to compare the incidence of idiopathic central precocious puberty (CPP) in our highly specialized Endocrinological Center before and after the onset of COVID-19 lockdown; we also aimed to identify any potential difference between
G. Goggi, M. Moro, A. Chila, L. Fatti, B. Cangiano, S. Federici, E. Galazzi, E. Carbone, D. Soranna, V. Vezzoli, L. Persani, M. Bonomi   +11 more
semanticscholar   +1 more source