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Genetic etiologies of central precocious puberty [PDF]
Pubertal onset is a complex process, which is influenced by genetic and environmental factors, such as obesity and endocrine-disrupting chemicals. In addition, the timing of normal puberty varies between individuals and is a highly polygenic trait with ...
Hae Sang Lee
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Precocious puberty in girls: a clinical case of idiopathic central precocious puberty
Central precocious puberty occupies an important place in the practice of a pediatric endocrinologist. If the patient reveals signs of premature sexual development, the diagnostic search is aimed at eliminating the tumor origin of both false (peripheral) and gonadotropin-dependent, or central, precocious puberty, as well as gonadotropin-independent ...
Olga V. Lagno +2 more
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Precocious puberty: a clinical review [PDF]
Precocious puberty is defined as pubertal development occurring more than 2.5 standard deviations earlier than the average age. It may comprise of central or gonadotropin-dependent precocious puberty and peripheral or gonadotropin-independent precocious ...
Samal, Rupal +3 more
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Ovarian cysts and tumors as the cause of isosexual pseudoprecocious puberty [PDF]
Introduction. Precocious puberty in girls is generally defined as appearance of secondary sexual characteristics before eight years of age. Menarche before the ninth birthday may serve as an additional criterion.
Mitrović Katarina +4 more
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Effect of gonadotropin-releasing hormone agonist treatment on near final height in girls with central precocious puberty and early puberty [PDF]
Purpose The aim of this study was to examine whether gonadotropin-releasing hormone (GnRH) agonist treatment is effective in preserving final height in patients with central precocious puberty (CPP) or early puberty (EP).
Eun Hye Yang +8 more
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The aim of this study was to elucidate the etiology and clinical features of Taiwanese girls with isosexual precocious puberty. 460 girls with precocious puberty were enrolled in this study.
李正婷;童怡靖;蔡文友 +1 more
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Central Precocious Puberty in a Child With Metachromatic Leukodystrophy [PDF]
Metachromatic leucodystrophy (MLD) is a rare inherited lysosomal disorder caused by reduced activity of the enzyme arylsulfatase A with accumulation of sulfatides in the nervous system. We report a female child affected by MLD who developed central precocious puberty (CPP). This association has not been described so far.
Gilda Belli +6 more
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Treatment of Peripheral Precocious Puberty
There are many etiologies of peripheral precocious puberty (PPP) with diverse manifestations resulting from exposure to androgens, estrogens, or both. The clinical presentation depends on the underlying process and may be acute or gradual.
Schoelwer, Melissa +3 more
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Precocious Puberty: Etiology and Current Treatment [PDF]
Precocious puberty also known as premature puberty is an abnormal pubertal development that can affect a child's growth and development. The clinical manifestations of precocious puberty are generally diverse and based on etiology are classified into ...
Ajmala, Indana Eva +8 more
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Central Precocious Puberty as a Sign of Congenital Adrenal Hyperplasia: Case Presentations [PDF]
Central precocious puberty results from the premature activation of the hypothalamic-pituitary-gonadal axis. Rarely congenital adrenal hyperplasia and/or its inappropriate treatment can be a peripheral cause of CPP.
Markosyan, R.L., Navasardyan, L.V.
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