Results 61 to 70 of about 6,072,229 (217)

Tanner stages of thelarche in relation to anthropometric and ultrasound predictors in premenarcheal girls

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
We found a close correlation between thelarche and internal genital maturation on pelvic ultrasound, paralleling Tanner breast stages and supporting the concept of correlated external and internal pubertal development. Abstract Introduction Thelarche is often the first sign of puberty initiation in girls.
Andrius Cekuolis, Zivile Sabonyte‐Balsaitiene, Eugenijus Jasiunas, Rytis Marozas, Janina Tutkuviene, Diana Ramasauskaite, Zana Bumbuliene   +6 more
wiley   +1 more source

Optimal therapy of pubertal disorders in precocious/early puberty

, 2001
. The possibility of progression of premature thelarche into precocious puberty, the pathogenesis of organic and idiopathic precocious puberty, the criteria for decision to treat and to stop treatment and the utility of an association with GH treatment ...
Tatò L., Savage M.O., Oostdijk W., Pasquino A.M., Raiola G., Saenger P., Tonini G., ANTONIAZZI, Franco, Voorhoeve P.G., Buzi F., Di Maio S., International Workshop on Management of Puberty for Optimum Auxological Results   +11 more
core   +1 more source

Associations between serum vitamin D levels and precocious puberty in girls [PDF]

Annals of Pediatric Endocrinology & Metabolism, 2014
PurposeVitamin D deficiency has been linked to chronic diseases, such as diabetes mellitus, obesity and autoimmune disease. However, data on the vitamin D status and its association with precocious puberty in girls are limited.
Hae Sang Lee, You Jin Kim, Young Seok Shim, Hwal Rim Jeong, Eunbyul Kwon, Jin Soon Hwang   +5 more
doaj   +1 more source

Diagnostic Yield of Brain MRI in Pediatric Short Stature: Hypothalamic–Pituitary Lesions and Incidental Findings in Real‐World Practice

Clinical Endocrinology, EarlyView.
ABSTRACT Background Brain MRI is widely performed in children with short stature or suspected growth hormone deficiency(GHD) to exclude hypothalamic–pituitary (HP) pathology, yet its diagnostic yield in routine practice is uncertain. We aimed to evaluate the prevalence, clinical significance, and distribution of HP and extrahypothalamic abnormalities ...
Mustafa Zubeidat, Tamer Sobeh, Shai Shrot   +2 more
wiley   +1 more source

Rare variants in the MECP2 gene in girls with central precocious puberty: a translational cohort study. [PDF]

, 2023
BACKGROUND: Identification of genetic causes of central precocious puberty have revealed epigenetic mechanisms as regulators of human pubertal timing.

core   +2 more sources

Serum vitamin D levels in girls with central precocious puberty

Pharmaceutical and Biomedical Research, 2018
Precocious puberty can cause several adverse effects on final growth and social behavior in girls. Recent studies showed that low serum level of vitamin D might be associated with precocious puberty.
Mohammadreza Rafati, Daniel Zamanfar, Seyedeh-Nesa RezaeianShiadeh, Fatemeh Faramarzi, Mohsen Aarabi, Hamid Rayati Damavandi   +5 more
doaj  

Clinical, Endocrine, and Neuroimaging Characteristics of Children with Central Precocious Puberty: A Single Tertiary Center Experience from Iraq [PDF]

Al-Anbar Medical Journal
Background: Puberty is a biological transition from childhood to sexual maturity. Early diagnosis and treatment of central precocious puberty (CPP) can slow the pace of puberty‚ delay bone age from advancement, too dramatically‚ and lead to timely ...
Noor Alhuda Hassan Jamgh, Wasnaa Hadi Abdullah   +1 more
doaj   +1 more source

Effects of childhood obesity and related genetic factors on precocious puberty: protocol for a multi-center prospective cohort study

BMC Pediatrics, 2022
Background Childhood obesity has important effects on the onset and development of puberty. Although a number of studies have confirmed the relationship between obesity and precocious puberty, little is known about the pleiotropic genes of obesity and ...
Tingting Yu, Ying Yu, Xiaoqing Li, Peng Xue, Xiaodan Yu, Yao Chen, Huijun Kong, Cuilan Lin, Xiumin Wang, Hao Mei, Dan Wang, Shijian Liu   +11 more
doaj   +1 more source

Pathogenicity of NUSAP1 Variants Is Defined by NMD‐Escape: Evidence From Two Novel Cases and Systematic Population‐Based Variant Analysis

Clinical Genetics, EarlyView.
Heterozygous de novo nonsense variants in the penultimate and last exons of NUSAP1 were identified in two unrelated individuals, predicted to escape NMD. In population data, nonsense variants were observed in exons 1–9 (of 11) in NUSAP1 but were absent from its 3′‐terminal region.
Maureen Jacob, Susann Badmann, Stefania Bigoni, Maria Iascone, Ilaria Vivaldi, Katharina Mayerhanser, Robert Kopajtich, Holger Prokisch, Cristina Forest, Sebastian Eck, Michael Zech, Elisabeth Graf, Matias Wagner, Juliane Winkelmann, Theresa Brunet, Melanie Brugger   +15 more
wiley   +1 more source

Causes and Types of Precocious Puberty in North-West Iran [PDF]

, 2013
Objective: Precocious puberty is of concern because of the underlying disorders, the short adult stature, and the psychosocial difficulties. This study was carried out in order to evaluate the characteristics of children referred to pediatric ...
Shiva, Siamak, Shiva, Shadi, Fayyazi, Afshin, Melikian, Armen   +3 more
core   +2 more sources