Results 71 to 80 of about 21,714 (253)

A Testicular Leydig Cell Tumor; An Uncommon Cause of Precocious Puberty: A Case Report With Secondary Central Precocious Puberty

Acta Medica Iranica, 2023
Sexual precocity in boys is defined as any sign of secondary sexual characteristics present before the age of 9. Leydig cell tumors of the testes are a rare cause of peripheral precocious puberty in boys.
Seyede Tahereh Mousavi, Farshad Zohrabi, Mohammadreza Farzaneh   +2 more
doaj  

A Testicular Leydig Cell Tumor; An Uncommon Cause of Precocious Puberty: A Case Report With Secondary Central Precocious Puberty [PDF]

Sexual precocity in boys is defined as any sign of secondary sexual characteristics present before the age of 9. Leydig cell tumors of the testes are a rare cause of peripheral precocious puberty in boys. Here, we report 8 years and 4-month-old boys with
Farzaneh, Mohammad Reza, Mousavi, Seyede Tahereh, Zohrabi, Farshad   +2 more
core   +1 more source

Rare variants in the MECP2 gene in girls with central precocious puberty: a translational cohort study.

, 2023
BACKGROUND: Identification of genetic causes of central precocious puberty have revealed epigenetic mechanisms as regulators of human pubertal timing.
Kaisinger, Lena R, Jordan E Read, Abreu, Ana Paula, Vinicius N Brito, Montenegro, LR, Canton, Ana PM, Latronico, Ana Claudia, Tinano, FR, Jesús Argente, Espino-Aguilar, R, Ong, Ken K, John R B Perry, Alexander A L Jorge, Escribano-Muñoz, Arancha, Fiona Ryan, Argente, J, Ursula B Kaiser, Argente, Jesús, Mariana P Piana, Brito, VN, Ken K Ong, Abreu, AP, Ong, KK, Kaiser, UB, Read, Jordan E, David, A, Gomes, LG, Silvia S Costa, Piana, MP, Canton, Ana P M, Jorge, Alexander A L, Howard, SR, Ana Claudia Latronico, Tinano, Flávia R, Berenice B Mendonca, Brauner, Raja, Sasha R Howard, Brito, Vinicius N, Melo, MED, Leonardo Guasti, Shears, Deborah, Maria Edna de Melo, Ryan, Fiona, Espino-Aguilar, Rafael, Perry, JRB, Paganoni, A, Perry, John RB, Perry, John R B, Ryan, F, Alyssa Paganoni, Costa, SS, Shears, D, Howard, Sasha R, de Melo, Maria Edna, Mendonca, Berenice B, Mendonca, BB, Carlos E Seraphim, Rafael Espino-Aguilar, Ana Cristina Krepischi, Montenegro, Luciana R, Paganoni, Alyssa, Krepischi, Ana Cristina, Larissa G Gomes, Kaiser, Ursula B, Kaisinger, LR, Arancha Escribano-Muñoz, Korbonits, Márta, Piana, Mariana P, Seraphim, CE, Deborah Shears, Gomes, Larissa G, Luciana R Montenegro, Márta Korbonits, Seraphim, Carlos E, Flávia R Tinano, Costa, Silvia S, Raja Brauner, Canton, APM, Ana Paula Abreu, Brauner, R, Alessia David, Krepischi, AC, Jorge, AAL, Guasti, Leonardo, Guasti, L, Escribano-Munoz, A, Read, JE, Korbonits, M, Jorge, Alexander AL, David, Alessia, Ana P M Canton, Lena R Kaisinger, Latronico, AC   +92 more
core   +2 more sources

Steroidopathies and hormonal imbalance in children and adolescents with autism spectrum disorder

JCPP Advances, EarlyView.
Abstract Background Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition with a multifactorial etiology, many aspects of which remain unclear. Emerging evidence suggests a potential association between ASD and clinical manifestations resulting from hormonal imbalances, henceforth named “steroidopathies.” The present study aims to ...
Concetta de Giambattista, Patrizia Ventura, Samuele Cortese, Paolo Trerotoli, Alessandra Di Gioia, Lucia Margari   +5 more
wiley   +1 more source

Gonadotropin-releasing hormone analogue and recombinant human growth hormone treatment for idiopathic central precocious puberty in girls

Frontiers in Endocrinology, 2022
Purpose To investigate the effectiveness and safety of gonadotropin-releasing hormone analogue (GnRHa) in combination with recombinant human growth hormone (rhGH) in girls with central precocious puberty (CPP). Methods Clinical data of 80 girls diagnosed
Yuzhen Shi, Ziyi Ma, Xi Yang, Yanqin Ying, Xiaoping Luo, L. Hou   +5 more
semanticscholar   +1 more source

Central Precocious Puberty as a Complication of Therapy with Adrenocorticotropin (ACTH) and an Aromatase Inhibitor for Refractory Nephrotic Syndrome

Case Reports in Pediatrics, 2019
Glucocorticoids are typically prescribed for the treatment of idiopathic nephrotic syndrome of childhood. In selected patients with refractory focal segmental glomuerulosclerosis (FSGS), adrenocorticotropin (ACTH) can be used to induce remission and ...
Sungeeta Agrawal, Robert Gensure, Lawrence Milner, Julie Nicoletta, Abdollah Sadeghi-Nejad   +4 more
doaj   +1 more source

Precocious Puberty: Etiology and Current Treatment

, 2023
Precocious puberty also known as premature puberty is an abnormal pubertal development that can affect a child's growth and development. The clinical manifestations of precocious puberty are generally diverse and based on etiology are classified into ...
Ajmala, Indana Eva, Fesmia, Herodya Lajunee, Wulandari, Ni Made Utami, Novsyaini, Zhayyin Palna Rial, Maulida, Adinda Ilsa, Rahmawati, Baiq Ayu, Nadila, Clara, Rahma, Jihan Alifa, Perwita, Alma Dyah   +8 more
core  

Precocious puberty in girls: a clinical case of idiopathic central precocious puberty

Pediatrician (St. Petersburg), 2021
Central precocious puberty occupies an important place in the practice of a pediatric endocrinologist. If the patient reveals signs of premature sexual development, the diagnostic search is aimed at eliminating the tumor origin of both false (peripheral) and gonadotropin-dependent, or central, precocious puberty, as well as gonadotropin-independent ...
Olga V. Lagno, Maria E. Turkunova, Elena B. Bashnina   +2 more
openaire   +1 more source

International Guideline on the Diagnosis and Management of Pediatric Patients With Hereditary Angioedema

Allergy, EarlyView.
ABSTRACT Hereditary angioedema (HAE) with C1 inhibitor deficiency is a rare disease characterized by unpredictable episodes of tissue swelling (angioedema), which, in most cases, occur first under the age of 18 years, and entail a significant burden of disease not only for the patients but also for their families.
Henriette Farkas, Inmaculada Martinez‐Saguer, Konrad Bork, Anastasios E. Germenis, Anete S. Grumach, Hanga Réka Horváth, Andrea Luczay, Andrea Zanichelli, Markus Magerl, Stephen Betschel, Emel Aygören‐Pürsün, Jonathan A. Bernstein, Isabelle Boccon‐Gibod, Teresa Caballero, Mauro Cancian, Sandra Christiansen, Danny M. Cohn, Francisco Contreras, Sansanee Craig, Camelia Isaic, Ankur Jindal, Constance H. Katelaris, Hilary J. Longhurst, Andrew MacGinnitie, Jonny Peter, Grzegorz Porebski, Avner Reshef, Dinh Van Nguyen, Bruce Zuraw, Anthony J. Castaldo, Henrik Balle Boysen, Timothy Craig, the Hereditary Angioedema Working Group (HAWK Group), Adil Adatia, Fiorella Adrianzen, Shimalee Andarawewa, Sladjana Andrejevic, Gabriel Emmanuel Arce‐Estrada, Ecem Ay, Adil Bahadir, Noemi Anna Bara, Marko Barešić, Krasimira Baynova, Shira Benor, Juliette Besson, Dharmagat Bhattarai, Patricia Bigas, Alexis Bocquet, Laurence Bouillet, Nicholas Brodszki, Thomas Buttgereit, Rosario Cabañas, Regis Campos, Asuman Çamyar, Orlane Chol, Stefan Cimbollek, Monica Colque Bayona, Cascia Day, Mats de Lange, Alex Fam, Davide Firinu, Tomas Freiberger, Johana Gil‐Serrano, Delphine Gobert, Dawn Goodyear, Maria del Mar Guilarte Clavero, Svetlana Hadvabova, David Hagin, Roman Hakl, George Harmat, Mensuda Hasanhodzic, Gocki Jacek, Joshua Jacobs, Rashmi Jain, Milos Jesenak, Amin Kanani, Daniela Kapustová, Boris Karanovic, Paul Keith, Tamar Kinaciyan, Pavlina Kralickova, Marcin Kurowski, Krzysztof Kuziemski, Rolando Laurel‐Laurel, Iris Leibovich‐Nassi, Gabriela Leon Zambrana, Ramon Lleonart, Lorena Lorenzo, Ferhat Maksudov, Ania Manson, Dusanka Markovic, Jayne McGucken, Nihal Mete Gokmen, Radovan Mijanovic, Vania Maria Miranda Saavedra, Irene Modestou, Sandra Nieto, Nora Nilsson, Patrik Nordenfelt, Francesca Perego, Angelica Petraroli, Elsa Phillips‐Angles, Alicia Prieto‐García, Michel Raguet, Marc Riedl, Matija Rijavec, Solange Rodrigues Valle, Yaryna Romanyshyn, Antoine Saut, Riccardo Senter, Branislav Šlenker, Marta Sobotkova, Peter J. Spaeth, Marcin Stobiecki, Linda Sundler Björkman, Mireille‐Maria Suttle, Agnes Szilágyi, Paola Triggianese, Kassiani Tzeli, Martina Vachová, Anna Valerieva, Solange Valle, Lilian Varga, Walter A. Wuillemin, Patrick Yong, Zhi Yuxiang, Liudmyla Zabrodska, Radana Zachova, Julia Zharankova   +128 more
wiley   +1 more source

Exploring the Mechanistic Interplay between Gut Microbiota and Precocious Puberty: A Narrative Review

Microorganisms
The gut microbiota has been implicated in the context of sexual maturation during puberty, with discernible differences in its composition before and after this critical developmental stage.
Min Yue, Lei Zhang
doaj   +1 more source