Results 51 to 60 of about 742,194 (304)

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Applying the Skip Navigation Links in the Context of the Websites’ Accessibility of Central Public Administration Bodies in the Trenčín Region [PDF]

Societas et Iurisprudentia, 2015
The study focuses in its main aim on seeking yet undetected or undefined deficits in relation to applying the skip navigation mechanism on the websites of the central public administration bodies in the Trenčín Region in the context of improving the ...
Jana Koprlová
doaj  

Organizational and Legal Mechanism of Public Administration of Functioning and Development of Electronic Consultations

Krakowskie Studia Małopolskie, 2020
quality of e-consultations; unwillingness of the subjects of power to allow the civil society to have a real impact on state affairs, lack of responsibility for ignor-ing the law in regard to organization and conduct of e-consultations, distrust of the ...
Ya. L. Yansons
semanticscholar   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Special Issue on Northern Ireland “Devolution, Governance and the Peace Process” [PDF]

, 2004
Devolution and the associated mechanisms of governance - a power-sharing Executive, elected Assembly, cross-border bodies, a reformed system of public administration and civic engagement, are part of the wider mosaic of peace building.
Carmichael, Paul, Knox, Colin
core  

The influence of ROS1 fusion partners and resistance mechanisms in ROS1‐TKI‐treated non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga, Christa Dijkhuizen, Patrick Korthuis, Wim Timens, Harry Groen, Jeroen Hiltermann, Anke van den Berg, Lyndsay Drayer, Anthonie van der Wekken   +8 more
wiley   +1 more source

Accounting and the management of internal interdependencies: 14th century archival sources from the Comune of Siena

JLIS.it, 2019
The aim of this study is to explore the role that accounting systems effectively played in managing the internal relationships among the various administrative bodies of the Comune (City State) of Siena in the 14th century.
Andrea Giorgi, Elena Giovannoni, Stefano Moscadelli, Angelo Riccaboni   +3 more
doaj   +9 more sources

Guatemala: «Culture, the driving force of its integral development» [PDF]

, 2014
El autor presenta una reflexión a propósito de la situación que vive en Guatemala el sector cultural. La gran diversidad y calidad del patrimonio guatemalteco no encuentran, en su opinión, los apoyos necesarios por parte de las administraciones ...
Araujo, Max
core   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Legitimacy as the basis of public administration

Analytical and Comparative Jurisprudence
The article is devoted to the study of legality and discipline as one of the central principles of modern legal systems, the law of the European Union, where Ukraine is also trying to integrate.
A. Chubai
semanticscholar   +1 more source