ADP‐ribosylation: An emerging regulator of the epigenome
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Computational pathology-based artificial intelligence platform for the identification of common oral potentially malignant disorders. [PDF]
Li L, Zhang J, Cai X.
europepmc +1 more source
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Evaluation of the Effectiveness of a Novel Wireless Energy-Transmitting Implantable Diaphragm Pacemaker in Anesthetized Pigs. [PDF]
Gu X, Zhong W, Mao Z, Shi Y, Wang Y.
europepmc +1 more source
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Diagnostic value of serum inhibin B, anti-Müllerian hormone, and estradiol for central precocious puberty and early-fast puberty in girls: a cross-sectional study. [PDF]
Xu L +6 more
europepmc +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Response Surface Analysis of Thermo-Hydraulic Performance of a Direct Absorption Solar Receiver Using Fe<sub>3</sub>O<sub>4</sub> Nanofluid Under Concentrated Solar Irradiation. [PDF]
Ham J, Kim H, Ryu SB, Cho H.
europepmc +1 more source
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
Wenjing Zhao,1,* Pan Yan,2,* Yi Pei,3,4,* Ying Xia,3 Yongfeng Zhu,3 Ming Lei,3 Li Shi,3 Xiaohua Ma,5 Jianhua Pan,5 Ping Deng,1 Yiping Leng6,7 1The Affiliated Changsha Central Hospital, Department of Cardiology, Hengyang Medical ...
Zhao W +10 more
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