Results 101 to 110 of about 12,663,351 (362)

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Central Venous Line and Acute Neurological Deficit: A Case Series

open access: yesJournal of Tehran University Heart Center, 2015
Central venous catheter (CVC) insertion is a practical way to assess patients hemodynamic specially in cardiovascular surgery but this relatively simple junior level procedure is not risk free and its common reported complications include; pneumothorax ...
SeyedHossein Ahmadi   +5 more
doaj  

Polyhedral Products, Graph Products, and $$p$$-Central Series

open access: yesProceedings of the Steklov Institute of Mathematics
We relate polyhedral products of topological spaces to graph products of groups. The loop homology algebras of polyhedral products are identified with the universal enveloping algebras of the Lie algebras associated with central series of graph products.
Panov, Taras E.   +1 more
openaire   +2 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Topical Nepafenac 0.1% or 0.3% for the Treatment of Central Serous Chorioretinopathy: A Case Series of Chronic and Recurrent Disease and Review of the Literature [PDF]

open access: diamond, 2022
Ishani Hariprasad   +6 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Odd Euler Sums and Harmonic Series with Cubic Central Binomial Coefficients in Denominators

open access: yesAxioms
By means of the coefficient extraction method, we examine a transformation of a classical hypergeometric series. Three classes of infinite series (of convergence rate “1/4”) with harmonic numbers in numerators and cubic central binomial coefficients in ...
Chunli Li, Wenchang Chu
doaj   +1 more source

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