Results 131 to 140 of about 1,090,342 (306)

The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity

FEBS Open Bio, EarlyView.
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda, Melissa Montrose, Akinori Takahashi, Risa Ishida, Sandrine Burriel, Nao Ohmine, Tohru Natsume, Shungo Adachi, Minsoo Kim, Tadashi Yamamoto   +9 more
wiley   +1 more source

Palynological Studies of the Alluvial Deposits in the Imizu Plain, Toyama Prefecture:The Alluvial Series in the Hokuriku District, Central Japan (Part I)

, 1965
Norio Fuji
openalex   +2 more sources

Taxonomy of Mexican and Central American Members of Solanum Series Conicibaccata (sect. Petota) [PDF]

, 2001
David M. Spooner, R.G. van den Berg, A. Rivera-Peña, Peter H. Velguth, Alfonso del Río, Alberto Salas-López   +5 more
openalex   +1 more source

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

FEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr, Michael Fauler, Thomas Zimmer, Bettina Jungwirth, Hubert Schrezenmeier, David Alexander Christian Messerer   +5 more
wiley   +1 more source

Drugs affecting the central nervous system. Vol. 2 of the Medicinal Research Series. Edited by Alfred Burger. Marcel Dekker, Inc., 95 Madison Ave., New York, NY 10016, 1968. xv + 437pp. 16 × 24cm. Price $19.75

, 1968
Raymond P. Ahlquist
openalex   +1 more source

On central series of a group

Journal of Algebra, 1967
openaire   +3 more sources

The modified Stack procedure for central slip reconstruction: a case series

Australasian Journal of Plastic Surgery
There are many surgical techniques for reconstruction of the divided or incompetent central slip. Most rely upon postoperative immobilisation to protect the repair.
James Warbrick-Smith, Holly Morris, Shirley Collocott, Amy Wang, Karen L Smith   +4 more
doaj   +1 more source

On the respective terms of the lower central series of a free group and a normal subgroup

, 1974
Dennis Spellman
openalex   +1 more source

Comparison of extremes in GCM-simulated, downscaled and observed central-European temperature series [PDF]

, 2002
Jan Kyselý
openalex   +1 more source

Precision‐Optimised Post‐Stroke Prognoses

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Current medicine cannot confidently predict who will recover from post‐stroke impairments. Researchers have sought to bridge this gap by treating the post‐stroke prognostic problem as a machine learning problem, reporting prediction error metrics across samples of patients whose outcomes are known.
Thomas M. H. Hope, Howard Bowman, Rachel M. Bruce, Alex P. Leff, Cathy J. Price   +4 more
wiley   +1 more source