Results 61 to 70 of about 1,090,342 (306)
On the length of the central series (derived series) of a moufang commutative loop [PDF]
Mathematical Notes, 1997 A loop \((Q,\cdot)\) is a Moufang commutative loop (MCL) if \(a^2\cdot bc=ab\cdot ac\) for all \(a,b,c\in Q\). The associator \([a,b,c]\) is defined by \(ab\cdot c=a[a,b,c]\cdot bc\). The lower (transfinite) central series of an MCL \(Q\) has the form \(Q=Q_0\supseteq Q_1\supseteq\cdots\supseteq Q_i\supseteq Q_{I=1}\supseteq\cdots\), where the normal ...
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Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
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Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
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Molecular Oncology, EarlyView.This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit +19 more
wiley +1 more source
On characterization of the hypercenters of fuzzy groups
Vìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Matematika, 2013 We continue the study of the properties of the upper central series for arbitrary fuzzy group. More precisely, a quite explicit description of the members of the upper central series has been obtained.
K.O. Grin
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Molecular Oncology, EarlyView.Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu +11 more
wiley +1 more source
Central Venous Line and Acute Neurological Deficit: A Case Series
Journal of Tehran University Heart Center, 2015 Central venous catheter (CVC) insertion is a practical way to assess patients hemodynamic specially in cardiovascular surgery but this relatively simple junior level procedure is not risk free and its common reported complications include; pneumothorax ...
SeyedHossein Ahmadi +5 more
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Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
An Update to the Central England Temperature Series—HadCET v2.1
Geoscience Data JournalThe Central England Temperature (CET) series is one of the longest instrumental climate records in the world. The CET record from 1659 represents a roughly triangular area of England extending from the Lancashire plain in the north, to London in the ...
Tim Legg +3 more
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