Results 61 to 70 of about 7,788 (192)

Characterization of retinal pigment epithelium layer in healthy and diseased retinas with high‐resolution adaptive optics transscleral flood illumination imaging

open access: yesActa Ophthalmologica, Volume 104, Issue 3, Page e277-e291, May 2026.
Abstract Purpose The retinal pigment epithelium (RPE) is critical in the pathophysiology of retinal diseases, such as age‐related macular degeneration. Adaptive optics transscleral flood illumination (AO‐TFI) offers rapid, detailed morphometric characterization of the RPE layer.
Leila Sara Eppenberger   +8 more
wiley   +1 more source

Phase II Trial of Opaganib Addition in Metastatic Castration‐Resistant Prostate Cancer After Disease Progression on Abiraterone or Enzalutamide

open access: yesCancer Medicine, Volume 15, Issue 4, April 2026.
This phase II trial investigated the safety and efficacy of opaganib in combination with abiraterone or enzalutamide in patients with castration‐resistant prostate cancer (CRPC). While the study did not meet its disease control efficacy endpoint, there was evidence of clinical activity in a subset of patients.
Jacqueline T. Brown   +12 more
wiley   +1 more source

Endogenous oestrogens as neuroprotective modulators in the human retina: Evidence from transcriptomic profiling and aromatase inhibition

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 4, April 2026.
Single‐cell transcriptomics reveals that the human retina expresses a broad repertoire of steroid hormone biosynthesis and estrogen signalling genes. Functional validation in retinal explants shows that local estrogen synthesis is neuroprotective, preventing photoreceptor death and limiting microglial activation. Abstract Steroid hormones, particularly
Antolin Canto   +6 more
wiley   +1 more source

Pretreatment characteristics of patients with central serous chorioretinopathy.

open access: yes, 2023
Pretreatment characteristics of patients with central serous chorioretinopathy.
Taiji Sakamoto (104961)   +6 more
core   +1 more source

Case series: The value of fundus autofluorescence in inherited macular disease

open access: yesOptometry and Vision Science, Volume 103, Issue 3, March 2026.
ABSTRACT Purpose To evaluate the diagnostic utility of fundus autofluorescence (FAF) imaging in identifying and characterizing phenotypically classified inherited macular dystrophies. In this way, we aim to provide methods by which eye care practitioners can link FAF imaging and other clinical results or imaging modalities to aid their clinical ...
Marina Guro   +6 more
wiley   +1 more source

Quetiapine associated Central Serous Chorioretinopathy: Implicit role of serotonin and dopamine pathways

open access: yesIndian Journal of Ophthalmology, 2019
A 30-year-old insomniac, an off-label user of quetiapine, presented with blurring of central vision, eventually diagnosed as central serous chorioretinopathy.
Manish Jain
doaj   +1 more source

Photodynamic Therapy with Verteporfin for Chronic Central Serous Chorioretinopathy: A Review of Data and Efficacy

open access: yesPharmaceuticals, 2020
Central serous chorioretinopathy represents the fourth most frequent retinal disorder, occurring especially in young age. Central serous chorioretinopathy is mainly characterized by macular serous retinal detachment and although the clinical course moves
Pierluigi Iacono   +3 more
doaj   +1 more source

Beyond Treatment: The Strategy of Nonintervention in Choroidal Hemangioma

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT The circumscribed choroidal hemangioma (CCH) is a benign congenital eye tumor whose etiology is not clear. A 41‐year‐old female patient came with a 2‐year history of slowly progressive deteriorating vision in her right eye. In the left eye, the best‐corrected visual acuity (BCVA) was 6/6, and counting fingers at 1 m in the right eye.
Humdan Khan   +8 more
wiley   +1 more source

Central Serous Chorioretinopathy Complicating Systemic Corticosteroid Therapy

open access: yes, 1997
Purpose. To present evidence that systemic corticosteroid therapy may cause central serous chorioretinopathy. Methods. A 20-year-old male with idiopathic thrombocytopenic purpura was examined during systemic treatment with corticosteroids (100 mg daily).
A.M. Abu El-Asrar
core   +1 more source

A 51‐year‐old female presenting with headache and vision loss

open access: yes
Headache: The Journal of Head and Face Pain, EarlyView.
Laurel Ovrom   +3 more
wiley   +1 more source

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