Results 51 to 60 of about 5,888 (160)

Long‐term follow‐up of chronic central serous chorioretinopathy patients receiving oral eplerenone and half‐dose photodynamic therapy in the SPECTRA trial: SPECTRA trial report No. 4

Acta Ophthalmologica, Volume 104, Issue 5, Page e565-e577, August 2026.
Abstract Purpose Assessing the 24‐month treatment outcome of half‐dose photodynamic therapy (PDT) or oral eplerenone in chronic central serous chorioretinopathy (cCSC). Methods Multicentre randomized clinical trial included cCSC patients from the SPECTRA trial who were randomized to receive half‐dose PDT or oral eplerenone.
Helena M. A. Feenstra, Issam El Mansori, Thomas J. van Rijssen, Roula Tsonaka, Roselie M. H. Diederen, Carel B. Hoyng, Reinier O. Schlingemann, Camiel J. F. Boon, Elon H. C. van Dijk   +8 more
wiley   +1 more source

Corticosteroid-Induced Central Serous Chorioretinopathy

Mutiara Medika, 2020
Central Serous Chorioretinopathy (CSC) is a condition where there is an accumulation of serous fluid in the retinal pigment epithelium layer. The abnormality in the retinal pigment layer of the eye causes vision loss and serous detachment.
Ade John Nursalim, Vera Sumual
doaj   +1 more source

Hypercortisolism: Causes, Consequences and Clinical Significance – A Review of Pathophysiology

Diabetes, Obesity and Metabolism, Volume 28, Issue S4, Page 3-16, August 2026.
ABSTRACT Hypercortisolism or Cushing syndrome is a heterogeneous clinical spectrum caused by chronic glucocorticoid excess, ranging from exogenous Cushing syndrome to rare endogenous aetiologies and the increasingly recognised entity of mild autonomous cortisol secretion (MACS). Physiological cortisol production is tightly regulated by the hypothalamic–
Mohamed Eldib, Francisco Emilio Fierro, Maria Ortega Abad, Ricardo Correa   +3 more
wiley   +1 more source

Beyond Sequence: Posttranslational Remodeling of Antigens in Autoimmunity

Immunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT Autoimmune responses are often attributed to failed tolerance to self‐proteins, yet protein expression alone cannot explain why certain antigens dominate disease, why autoreactivity emerges under stress, or why specific HLA alleles shape risk.
Cynthiya Shrestha, Holly M. Weisfelder, Thanh D. Do   +2 more
wiley   +1 more source

Repeatability of SpotChecks contrast sensitivity test in macular disease

Optometry and Vision Science, Volume 103, Issue 7, July 2026.
ABSTRACT Purpose SpotChecks is an accessible contrast sensitivity test with good repeatability in healthy adults. This study compared its intra‐visit repeatability with the near Pelli–Robson test in adults with macular disease. Methods One eye from 29 adults with macular disease (mean age 71 ± 13 years) underwent high‐contrast logMAR acuity and two ...
Katlyn B. Sprague, Yabo Niu, Petros E. Carvounis, Nimesh B. Patel, Han Cheng   +4 more
wiley   +1 more source

Quetiapine associated Central Serous Chorioretinopathy: Implicit role of serotonin and dopamine pathways

Indian Journal of Ophthalmology, 2019
A 30-year-old insomniac, an off-label user of quetiapine, presented with blurring of central vision, eventually diagnosed as central serous chorioretinopathy.
Manish Jain
doaj   +1 more source

Photodynamic Therapy with Verteporfin for Chronic Central Serous Chorioretinopathy: A Review of Data and Efficacy

Pharmaceuticals, 2020
Central serous chorioretinopathy represents the fourth most frequent retinal disorder, occurring especially in young age. Central serous chorioretinopathy is mainly characterized by macular serous retinal detachment and although the clinical course moves
Pierluigi Iacono, Stefano Da Pozzo, Monica Varano, Mariacristina Parravano   +3 more
doaj   +1 more source

Exudative Retinal Detachments: A Rare Adverse Effect of Topiramate

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Topiramate‐induced multifocal exudative retinal detachment is a rare but potentially vision‐threatening adverse effect. We report a 59‐year‐old woman with idiopathic intracranial hypertension who developed painless bilateral blurry vision and color desaturation 8 days after initiation of topiramate 25 mg twice daily.
Sarah Aljefri, Meshal Alzakari, Bailasan Milibari, Doaa Milibari   +3 more
wiley   +1 more source

[Central serous chorioretinopathy (CSC)].

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2010
In the acute stage central serous chorioretinopathy (CSC) is characterized by serous retinal detachment. Monofocal or multifocal structural changes of the pigment epithelium layer are common. Unilateral blurred vision is the major clinical symptom. The pathogenesis is unclear but corticosteroids and stress may trigger the disease.
Baraki, H., Feltgen, Nicolas, Roider, J., Hoerauf, Hans, Klatt, C.   +4 more
openaire   +2 more sources

Foundation Models in Diagnosis of Ophthalmic Diseases: Construction and Application

Eye &ENT Research, Volume 3, Issue 2, Page 45-58, June 2026.
ABSTRACT Artificial intelligence holds promise for addressing the uneven distribution of medical resources across different regions. Compared with convolutional neural network models, foundation models offer significant advantages: on one hand, their pre‐training does not rely on massive labeled data; on the other hand, they possess the capability to ...
Xiaolu Huang, Guanran Zhang, Jiayu Xu, Shuyang Chen, Yanrong Li, Xiaodong Sun, Yanlin Qu, Huixun Jia   +7 more
wiley   +1 more source