Results 81 to 90 of about 14,512 (238)
Vogt-Koyanagi-Harada syndrome - current perspectives [PDF]
, 2016 Vogt-Koyanagi-Harada syndrome is a cause of noninfectious panuveitis, leading to significant vision loss in many patients. It is an autoimmune disease occurring in genetically susceptible individuals and clinically presents as bilateral panuveitis with ...
Baltmr, A +2 more
core +1 more source
BMC Ophthalmology, 2019 Purpose Central serous chorioretinopathy (CSCR) is a complex ocular entity that, in its chronic form, can lead to serious visual impairment and morphological damage to the retina.
Maciej Gawęcki +4 more
doaj +1 more source
Pharmacology Research &Perspectives, Volume 13, Issue 4, August 2025.Preclinical evaluation of the oral toxicity, genotoxicity, and safety pharmacology of LPM4870108. ABSTRACT Tropomyosin receptor kinase (Trk) inhibitors are an essential class of anticancer drugs treating NTRK gene fusions‐positive cancer. However, the potential for the emergence of on‐target resistance suggests newer Trk inhibitors with low drug ...
Xiaochen Zhang +6 more
wiley +1 more source
Morphologic Criteria of Lesion Activity in Neovascular Age-Related Macular Degeneration: A Consensus Article [PDF]
, 2017 Intravitreal antivascular endothelial growth factor drugs represent the current standard of care for neovascular age-related macular degeneration (nAMD).
Elena Gusson +8 more
core +1 more source
Safety of an Intravitreal Bevacizumab Biosimilar (MVASI)
Clinical &Experimental Ophthalmology, Volume 53, Issue 5, Page 523-528, July 2025.ABSTRACT Background Intravitreal bevacizumab has been used off‐label to treat multiple ocular conditions for almost two decades. Reference bevacizumab, Avastin, was discontinued in Australia in 2021. A bevacizumab biosimilar, MVASI, was approved by the Therapeutic Goods Administration for the treatment of metastatic cancer in 2020.
Hanru Wang +8 more
wiley +1 more source
Central Serous Chorioretinopathy: Pathogenesis and Management
Clinical Ophthalmology, 2019 Francesco Semeraro,1 Francesco Morescalchi,1 Andrea Russo,1 Elena Gambicorti,1 Andrea Pilotto,2 Francesco Parmeggiani,3 Silvia Bartollino,4 Ciro Costagliola4 1Department of Medical and Surgical Specialties, Radiological Sciences and Public Health ...
Semeraro F +7 more
doaj
Animal Models and Experimental Medicine, Volume 8, Issue 6, Page 1080-1094, June 2025.The present study investigates the role of the NLRP3 inflammasome in the chronicity of ocular inflammation in uveitis using the experimental autoimmune uveitis (EAU) model. Whole eyes collected from EAU mice, 12 weeks post induction, were sectioned and subjected to immunohistochemistry. The confocal images from these sections were then assessed for the
Avik Shome +3 more
wiley +1 more source
American Journal of Ophthalmology Case ReportsPurpose: To report an unusual case of a patient with intractable central serous chorioretinopathy with a dramatic treatment response to high-dose intravitreal aflibercept. Methods: Retrospective case report.
Jonathan B. Lin, Loh-Shan B. Leung
doaj +1 more source
Australasian Journal of Ultrasound in Medicine, Volume 28, Issue 2, May 2025.ABSTRACT Introduction Central serous chorioretinopathy (CSCR) is a common cause of acute, monocular vision loss amongst men aged 40–50 years. Diagnosis is typically multimodal, requiring advanced ophthalmic imaging. These techniques are not readily available in acute care settings.
Christian P. Pappas +3 more
wiley +1 more source
Improved in vivo imaging of human blood circulation in the chorioretinal complex using phase variance method with new phase stabilized 1 μm swept-source optical coherence tomography (pv-SSOCT) [PDF]
, 2014 We demonstrate the feasibility of our newly developed phase stabilized high-speed (100 kHz A-scans/s) 1 μm sweptsource optical coherence tomography (SSOCT) system with the phase-variance based motion contrast method for visualization of human ...
Kim, Dae Yu +3 more
core +1 more source